[HTML][HTML] Obesogens: How they are identified and molecular mechanisms underlying their action

N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …

[HTML][HTML] Adipotropic effects of heavy metals and their potential role in obesity

AA Tinkov, M Aschner, T Ke, B Ferrer, JC Zhou… - Faculty …, 2021 - ncbi.nlm.nih.gov
Epidemiological studies demonstrated an association between heavy metal exposure and
the incidence of obesity and metabolic syndrome. However, the particular effects of metal …

[HTML][HTML] The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

B Wang, EE Tsakiridis, S Zhang, A Llanos… - Nature …, 2021 - nature.com
Obesity results from a caloric imbalance between energy intake, absorption and
expenditure. In both rodents and humans, diet-induced thermogenesis contributes to energy …

[HTML][HTML] Choice of laboratory rodent diet may confound data interpretation and reproducibility

MA Pellizzon, MR Ricci - Current developments in nutrition, 2020 - Elsevier
The reproducibility of experimental data is challenged by many factors in both clinical and
preclinical research. In preclinical studies, several factors may be responsible, and diet is …

[HTML][HTML] Association between heavy metals, metalloids and metabolic syndrome: new insights and approaches

AC Martins, B Ferrer, AA Tinkov, S Caito… - Toxics, 2023 - mdpi.com
Metabolic syndrome (MetS) is an important public health issue that affects millions of people
around the world and is growing to pandemic-like proportions. This syndrome is defined by …

Combined threats of climate change and contaminant exposure through the lens of bioenergetics

ML Grunst, AS Grunst, D Grémillet… - Global Change …, 2023 - Wiley Online Library
Organisms face energetic challenges of climate change in combination with suites of natural
and anthropogenic stressors. In particular, chemical contaminant exposure has neurotoxic …

[HTML][HTML] Decoupling the adsorption mechanisms of arsenate at molecular level on modified cube-shaped sponge loaded superparamagnetic iron oxide nanoparticles

XY Lou, R Boada, V Verdugo, L Simonelli… - journal of environmental …, 2022 - Elsevier
In this study, a commercial cube-shaped open-celled cellulose sponge adsorbent was
modified by in-situ co-precipitation of superparamagnetic iron oxide nanoparticles (SPION) …

Heavy metal-induced lipogenic gene aberration, lipid dysregulation and obesogenic effect: a review

Y Zhou, FP Addai, X Zhang, Y Liu, Y Wang… - Environmental …, 2022 - Springer
Lipids are high energy, complex biomolecular compounds essential for cellular and
organellar membrane formation. Accumulation of circulatory lipids is however associated …

Impaired white adipose tissue fatty acid metabolism in mice fed a high-fat diet worsened by arsenic exposure, primarily affecting retroperitoneal adipose tissue

D Calderón-DuPont, SL Romero-Córdoba… - Toxicology and Applied …, 2023 - Elsevier
Fatty acid (FA) metabolism dysfunction of white adipose tissue (WAT) underlies obesity and
insulin resistance in response to high calorie intake and/or endocrine-disrupting chemicals …

SOX2 modulated astrocytic process plasticity is involved in arsenic-induced metabolic disorders

Z He, Y Xu, Q Ma, C Zhou, L Yang, M Lin… - Journal of Hazardous …, 2022 - Elsevier
Metabolic disorders induced by arsenic exposure have attracted great public concern.
However, it remains unclear whether hypothalamus-based central regulation mechanisms …