Golgi defect as a major contributor to lysosomal dysfunction

SR Akaaboune, Y Wang - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
The Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of
lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell …

Electron Capture vs Transfer Dissociation for Site Determination of Tryptic Peptide Tyrosine Sulfation: Direct Detection of Fibrinogen Sulfation Sites and Identification …

MM Youssef, CW Szot, J Folz, LM Collier… - Journal of Proteome …, 2024 - ACS Publications
Tyrosine sulfation, an understudied but crucial post-translational modification, cannot be
directly detected in conventional nanoflow liquid chromatography-tandem mass …

Negative-Ion Electron Capture Dissociation of MALDI-Generated Peptide Anions

SA DeFiglia, CW Szot, K Håkansson - Analytical Chemistry, 2024 - ACS Publications
Negative-ion electron capture dissociation (niECD) is an anion MS/MS technique that
provides fragmentation analogous to conventional ECD, including high peptide sequence …