Although Michael acceptors display a potent and broad spectrum of bioactivity, they have
largely been ignored in drug discovery because of their presumed indiscriminate reactivity …

Global hardness and softness and the associated hard/soft acid/base (HSAB) principle have
been used to explain many experimental observed reactivity patterns and these concepts …

Methylglyoxal (MGO) is a highly reactive ɑ-dicarbonyl compound that may adversely impact
food quality and human health by modifying proteins. The kinetics of the reaction of …

In this work, based on bis (tetrathiafulvalenyldithio)-germane (bis-TTF-Ge), 37 compounds
(denoted T0–T36) are designed by the introduction of donor and acceptor groups at different …

The kinetics of the reaction between methylglyoxal (MGO) and epigallocatechin gallate have
been investigated at pH 7.4 and 37° C, and the kinetic data were combined with previously …

The global and local electrophilicity indexes have been used to characterize the reactivity
pattern of the C C double bond towards nucleophilic addition reactions. A wide family of …

The novel 4H-pyran namely 2-Amino-6, 6-diméthyl-5-oxo-4-(4-méthoxyphenyl)-5, 6, 7, 8-
tetrahydro-4H-benzopyran-3-carbonitrile (HL1) and 2-Amino-6, 6-diméthyl-5-oxo-4-(phenyl) …

Density functional theory calculations at the B3LYP level are performed to theoretically
investigate the antioxidant properties of 30 thiaflavan compounds. The main theoretical …

The hard/soft acid− base (HSAB) principle has long been known to be an excellent predictor
of chemical reactivity. The Fukui function, a reactivity descriptor from conceptual density …

Abstract The title compound, 8-(3-chloropropanamido) quinolin-1-ium chloride,(C 12 H 11
ClN 2 O)+· Cl−(Q1), was synthesized via the reaction of quinolin-8-amine with 3 …