Spheroids in Cancer Research: Recent Advances and Opportunities

S Arora, S Singh, A Mittal, N Desai, DK Khatri… - Journal of Drug Delivery …, 2024 - Elsevier
In recent years, three-dimensional (3D) spheroid technology has emerged as a crucial
instrument in the realm of cancer research, offering a near-physiological model for probing …

Essential tremor: A three-dimensional neurosphere in vitro model to assess the neurotoxicity of harmane

R Aro, A Nachtergael, L Ris, M Manto… - Journal of Traditional …, 2023 - Elsevier
Objectives To use a novel in vitro model of three-dimensional (3D) neurosphere cultures to
assess neurotoxic or neuroprotective effects with harmane as a model compound. Methods …

[PDF][PDF] Journal of Traditional Chinese Medical Sciences

R Aro, A Nachtergael, L Ris, M Manto, P Duez - 2019 - researchgate.net
abstract Objectives: Considering that the 3 Rs of regulation (replacing, reducing, and
refining) are meant to reduce the number and suffering of research animals and that current …