Nanopore-based technologies beyond DNA sequencing

YL Ying, ZL Hu, S Zhang, Y Qing, A Fragasso… - Nature …, 2022 - nature.com
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Cu and Cu-based nanoparticles: synthesis and applications in catalysis

MB Gawande, A Goswami, FX Felpin, T Asefa… - Chemical …, 2016 - ACS Publications
The applications of copper (Cu) and Cu-based nanoparticles, which are based on the earth-
abundant and inexpensive copper metal, have generated a great deal of interest in recent …

Electrochemical sensing at a confined space

SM Lu, YY Peng, YL Ying, YT Long - Analytical chemistry, 2020 - ACS Publications
Single entity sensing is recently an area of tremendous interest in analytical chemistry, such
that it is possible to analyze single cells, single particles, and even single molecules. Among …

Nanopore sequencing: from imagination to reality

H Bayley - Clinical chemistry, 2015 - academic.oup.com
DNA sequencing and hence genomics have been transformed over the last decade by the
commercialization of inexpensive, massively parallel, short-read sequencing technology …

Distinct functional elements for outer-surface anti-interference and inner-wall ion gating of nanochannels

P Gao, Q Ma, D Ding, D Wang, X Lou, T Zhai… - Nature …, 2018 - nature.com
Over the decades, widespread advances have been achieved on nanochannels, including
nanochannel-based DNA sequencing, single-molecule detection, smart sensors, and …

Role of outer surface probes for regulating ion gating of nanochannels

X Li, T Zhai, P Gao, H Cheng, R Hou, X Lou… - Nature …, 2018 - nature.com
Nanochannels with functional elements have shown promise for DNA sequencing, single-
molecule sensing, and ion gating. Ionic current measurement is currently a benchmark, but …

Directional conformer exchange in dihydrofolate reductase revealed by single-molecule nanopore recordings

NS Galenkamp, A Biesemans, G Maglia - Nature Chemistry, 2020 - nature.com
Conformational heterogeneity is emerging as a defining characteristic of enzyme function.
However, understanding the role of protein conformations requires their thermodynamic and …

Single‐Molecule Determination of the Isomers of d‐Glucose and d‐Fructose that Bind to Boronic Acids

WJ Ramsay, H Bayley - Angewandte Chemie, 2018 - Wiley Online Library
Monosaccharides, such as d‐glucose and d‐fructose, exist in aqueous solution as an
equilibrium mixture of cyclic isomers and can be detected with boronic acids by the …

Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

Single-molecule sensing inside stereo-and regio-defined hetero-nanopores

W Liu, Q Zhu, CN Yang, YH Fu, JC Zhang, MY Li… - Nature …, 2024 - nature.com
Heteromeric pore-forming proteins often contain recognition patterns or stereospecific
selection filters. However, the construction of heteromeric pore-forming proteins for single …