Current advances in multifunctional nanocarriers based on marine polysaccharides for colon delivery of food polyphenols
S Tie, M Tan - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Inflammatory bowel disease (IBD) has been considered as a chronic disease that is difficult
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …
Airway mucus in pulmonary diseases: Muco-adhesive and muco-penetrating particles to overcome the airway mucus barriers
Airway mucus is a complex viscoelastic gel that provides a defensive physical barrier and
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …
An overview of the biochemistry, synthesis, modification, and evaluation of mucoadhesive polymeric nanoparticles for oral delivery of bioactive compounds
Mucoadhesion has been demonstrated to be a tangible strategy for designing oral delivery
systems with advantages over other existing systems such as increased local retention and …
systems with advantages over other existing systems such as increased local retention and …
Oral mucus-penetrating PEGylated liposomes to improve drug absorption: Differences in the interaction mechanisms of a mucoadhesive liposome
We investigated the feasibility of densely polyethylene glycol (PEG2000)-modified
liposomes as mucus-penetrating particles (MPPs) for oral delivery of systemically absorbed …
liposomes as mucus-penetrating particles (MPPs) for oral delivery of systemically absorbed …
Targeting mucus barrier in respiratory diseases by chemically modified advanced delivery systems
Mucus gel constitutes of heavily cross-linked mucin fibers forming a viscoelastic, dense
porous network that coats all the exposed epithelia not covered with the skin. The layer …
porous network that coats all the exposed epithelia not covered with the skin. The layer …
Nanocarrier-based approaches to combat chronic obstructive pulmonary disease
Abnormalities in airway mucus lead to chronic disorders in the pulmonary system such as
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …
Tadpole-Like Anisotropic Polymer/Lipid Janus Nanoparticles for Nose-to-Brain Drug Delivery: Importance of Geometry, Elasticity on Mucus-Penetration Ability
B Okmen Altas, GD Kalaycioglu… - Molecular …, 2024 - ACS Publications
Asymmetric geometry (aspect ratio> 1), moderate stiffness (ie, semielasticity), large surface
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …
Nanostructures for drug delivery in respiratory diseases therapeutics: Revision of current trends and its comparative analysis
LÁ Ibarra-Sánchez, A Gámez-Méndez… - Journal of Drug Delivery …, 2022 - Elsevier
Respiratory diseases are leading causes of death and disability in developing and
developed countries. The burden of acute and chronic respiratory diseases has been rising …
developed countries. The burden of acute and chronic respiratory diseases has been rising …
Recent advances on drug delivery applications of mucopenetrative/mucoadhesive particles: A review
The human body is made up of various external skin barriers to fight disease and infection.
One such barrier is mucus, which not only protects and lubricates the exposed epithelia by …
One such barrier is mucus, which not only protects and lubricates the exposed epithelia by …
Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport
V Lenders, X Koutsoumpou, P Phan… - Chemical Society …, 2023 - pubs.rsc.org
The biomedical use of nanoparticles (NPs) has been the focus of intense research for over a
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …