Inflammatory bowel disease (IBD) has been considered as a chronic disease that is difficult
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …

Airway mucus is a complex viscoelastic gel that provides a defensive physical barrier and
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …

Mucoadhesion has been demonstrated to be a tangible strategy for designing oral delivery
systems with advantages over other existing systems such as increased local retention and …

We investigated the feasibility of densely polyethylene glycol (PEG2000)-modified
liposomes as mucus-penetrating particles (MPPs) for oral delivery of systemically absorbed …

Mucus gel constitutes of heavily cross-linked mucin fibers forming a viscoelastic, dense
porous network that coats all the exposed epithelia not covered with the skin. The layer …

Abnormalities in airway mucus lead to chronic disorders in the pulmonary system such as
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …

Asymmetric geometry (aspect ratio> 1), moderate stiffness (ie, semielasticity), large surface
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …

Respiratory diseases are leading causes of death and disability in developing and
developed countries. The burden of acute and chronic respiratory diseases has been rising …

The human body is made up of various external skin barriers to fight disease and infection.
One such barrier is mucus, which not only protects and lubricates the exposed epithelia by …

The biomedical use of nanoparticles (NPs) has been the focus of intense research for over a
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …