Mucus and its movements are essential to epithelial tissue immune defenses against
pathogens, including fungal pathogens, which can infect respiratory, gastrointestinal or the …

While further research is required to clarify the extent of TSLP contribution in CRSwNP, this
review highlights the potential of anti-TSLP therapies as a novel approach for managing …

The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

Chronic rhinosinusitis (CRS) is a heterogenic disease characterized by persistent mucosal
inflammation of the upper airway. Researches of CRS have progressed from phenotype …

Background The airway epithelium plays a central role in the pathogenesis of chronic
respiratory diseases such as asthma and chronic rhinosinusitis with nasal polyps …

Recent advancements in medical management, endoscopic sinus surgery, and biologics
have significantly improved outcomes for patients with chronic rhinosinusitis (CRS) …

The lungs serve as the primary organ for respiration, facilitating the vital exchange of gases
with the bloodstream. Given their perpetual exposure to external particulates and …

Introduction Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the sinonasal
mucosa with distinct endotypes including type 2 (T2) high eosinophilic CRS with nasal …

Purpose Asthma is a chronic inflammatory disease influenced by complex genetic and
environmental factors. Despite extensive research, the intricate pathophysiology of asthma …

Background Basal cell hyperplasia is commonly observed in nasal polyp epithelium of
eosinophilic chronic rhinosinusitis (eCRS). We examined the function and mechanisms of …