Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

B Kocaadam, N Şanlier - Critical reviews in food science and …, 2017 - Taylor & Francis
Turmeric (Curcuma longa) is a type of herb belonging to ginger family, which is widely
grown in southern and south western tropical Asia region. Turmeric, which has an …

Potential role of curcumin and its nanoformulations to treat various types of cancers

MT Kabir, MH Rahman, R Akter, T Behl, D Kaushik… - Biomolecules, 2021 - mdpi.com
Cancer is a major burden of disease globally. Each year, tens of millions of people are
diagnosed with cancer worldwide, and more than half of the patients eventually die from it …

Curcumin, a component of golden spice: from bedside to bench and back

S Prasad, SC Gupta, AK Tyagi, BB Aggarwal - Biotechnology advances, 2014 - Elsevier
Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of
years, it is only within the past century that we learned about the chemistry of its active …

Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Curcumin and its derivatives as potential therapeutic agents in prostate, colon and breast cancers

Z Mbese, V Khwaza, BA Aderibigbe - Molecules, 2019 - mdpi.com
Cancer is a life-threatening disease and is the second leading cause of death around the
world. The increasing threats of drug-resistant cancers indicate that there is an urgent need …

Effect of different oleogelators on lipolysis and curcuminoid bioaccessibility upon in vitro digestion of sunflower oil oleogels

S Calligaris, M Alongi, P Lucci, M Anese - Food chemistry, 2020 - Elsevier
Sunflower oil enriched with curcuminoid compounds (CUs) was gelled by adding 5%(w/w)
saturated monoglycerides (MG), rice bran waxes (RW) or a mixture of β-sitosterol and γ …

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

JX Song, YR Sun, I Peluso, Y Zeng, X Yu, JH Lu, Z Xu… - Autophagy, 2016 - Taylor & Francis
Autophagy dysfunction is a common feature in neurodegenerative disorders characterized
by accumulation of toxic protein aggregates. Increasing evidence has demonstrated that …

Role of endoplasmic reticulum stress in the anticancer activity of natural compounds

P Limonta, RM Moretti, M Marzagalli, F Fontana… - International journal of …, 2019 - mdpi.com
Cancer represents a serious global health problem, and its incidence and mortality are
rapidly growing worldwide. One of the main causes of the failure of an anticancer treatment …

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer

M Shakibaei, P Kraehe, B Popper, P Shayan, A Goel… - BMC cancer, 2015 - Springer
Background To overcome the limitations of animal-based experiments, 3D culture models
mimicking the tumor microenvironment in vivo are gaining attention. Herein, we investigated …

Apoptotic pathway as the therapeutic target for anticancer traditional Chinese medicines

W An, H Lai, Y Zhang, M Liu, X Lin… - Frontiers in pharmacology, 2019 - frontiersin.org
Cancer is a leading cause of morbidity and mortality worldwide. Apoptosis is a process of
programmed cell death and it plays a vital role in human development and tissue …