From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
The lymphatic system in disease processes and cancer progression
TP Padera, EFJ Meijer, LL Munn - Annual review of biomedical …, 2016 - annualreviews.org
Advances in our understanding of the structure and function of the lymphatic system have
made it possible to identify its role in a variety of disease processes. Because it is involved …
made it possible to identify its role in a variety of disease processes. Because it is involved …
Lymphatic targeting by albumin-hitchhiking: applications and optimisation
M Abdallah, OO Müllertz, IK Styles, A Mörsdorf… - Journal of Controlled …, 2020 - Elsevier
The lymphatic system plays an integral role in the development and progression of a range
of disease conditions, which has impelled medical researchers and clinicians to design …
of disease conditions, which has impelled medical researchers and clinicians to design …
Immunology of lymphatic filariasis
S Babu, TB Nutman - Parasite immunology, 2014 - Wiley Online Library
The immune responses to filarial parasites encompass a complex network of innate and
adaptive cells whose interaction with the parasite underlies a spectrum of clinical …
adaptive cells whose interaction with the parasite underlies a spectrum of clinical …
Lymphatic dysfunction, leukotrienes, and lymphedema
X Jiang, MR Nicolls, W Tian… - Annual review of …, 2018 - annualreviews.org
The lymphatic system is essential for the maintenance of tissue fluid homeostasis,
gastrointestinal lipid absorption, and immune trafficking. Whereas lymphatic regeneration …
gastrointestinal lipid absorption, and immune trafficking. Whereas lymphatic regeneration …
Biological basis of therapeutic lymphangiogenesis
C Norrmén, T Tammela, TV Petrova, K Alitalo - Circulation, 2011 - Am Heart Assoc
The lymphatic and blood vascular systems function in concert to regulate the tissue fluid
homeostasis of the body. The pumping force of the heart generates a hydrostatic pressure …
homeostasis of the body. The pumping force of the heart generates a hydrostatic pressure …
Immunopathogenesis of lymphatic filarial disease
S Babu, TB Nutman - Seminars in immunopathology, 2012 - Springer
Although two thirds of the 120 million people infected with lymph-dwelling filarial parasites
have subclinical infections,∼ 40 million have lymphedema and/or other pathologic …
have subclinical infections,∼ 40 million have lymphedema and/or other pathologic …
[HTML][HTML] Filariasis in Africa—treatment challenges and prospects
Lymphatic filariasis (LF) and onchocerciasis are parasitic nematode infections that are
responsible for a major disease burden in the African continent. Disease symptoms are …
responsible for a major disease burden in the African continent. Disease symptoms are …
Insights into the pathogenesis of disease in human lymphatic filariasis
TB Nutman - Lymphatic research and biology, 2013 - liebertpub.com
Although two thirds of the 120 million people infected with lymph-dwelling filarial parasites
have subclinical infections,∼ 40 million have lymphedema and/or other pathologic …
have subclinical infections,∼ 40 million have lymphedema and/or other pathologic …
Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis
S Chakraborty, M Gurusamy, DC Zawieja… - …, 2013 - Wiley Online Library
Lymphatic filariasis, one of the most debilitating diseases associated with the lymphatic
system, affects over a hundred million people worldwide and manifests itself in a variety of …
system, affects over a hundred million people worldwide and manifests itself in a variety of …