[HTML][HTML] Genetics of attention deficit hyperactivity disorder

SV Faraone, H Larsson - Molecular psychiatry, 2019 - nature.com
Decades of research show that genes play an vital role in the etiology of attention deficit
hyperactivity disorder (ADHD) and its comorbidity with other disorders. Family, twin, and …

ADHD: Current concepts and treatments in children and adolescents

R Drechsler, S Brem, D Brandeis, E Grünblatt… - …, 2020 - thieme-connect.com
Attention deficit hyperactivity disorder (ADHD) is among the most frequent disorders within
child and adolescent psychiatry, with a prevalence of over 5%. Nosological systems, such as …

Identification of common genetic risk variants for autism spectrum disorder

J Grove, S Ripke, TD Als, M Mattheisen, RK Walters… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

[PDF][PDF] Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

FK Satterstrom, JA Kosmicki, J Wang, MS Breen… - Cell, 2020 - cell.com
We present the largest exome sequencing study of autism spectrum disorder (ASD) to date
(n= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …

[HTML][HTML] Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan

B Franke, G Michelini, P Asherson… - European …, 2018 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is highly heritable and the most common
neurodevelopmental disorder in childhood. In recent decades, it has been appreciated that …

Updated European Consensus Statement on diagnosis and treatment of adult ADHD

JJS Kooij, D Bijlenga, L Salerno, R Jaeschke… - European …, 2019 - cambridge.org
Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common
psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

D Demontis, RK Walters, J Martin, M Mattheisen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

[HTML][HTML] A review of heterogeneity in attention deficit/hyperactivity disorder (ADHD)

Y Luo, D Weibman, JM Halperin, X Li - Frontiers in human …, 2019 - frontiersin.org
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects
approximately 8%-12% of children worldwide. Throughout an individual's lifetime, ADHD …

Psychiatric genomics: an update and an agenda

PF Sullivan, A Agrawal, CM Bulik… - American Journal of …, 2018 - Am Psychiatric Assoc
The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of
psychiatry. This global effort is dedicated to rapid progress and open science, and in the …

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and …

J Zheng, AM Erzurumluoglu, BL Elsworth… - …, 2017 - academic.oup.com
Motivation LD score regression is a reliable and efficient method of using genome-wide
association study (GWAS) summary-level results data to estimate the SNP heritability of …