Lipids play important roles in energy metabolism along with diverse aspects of biological
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …

The basic helix-loop-helix-PAS transcription factor (CLOCK, Circadian locomotor output
cycles protein kaput) was discovered in 1994 as a circadian clock. Soon after its discovery …

Along evolution, living organisms developed a precise timekeeping system, circadian
clocks, to adapt life to the 24-h light/dark cycle and temporally regulate physiology and …

Silver nanoparticles (AgNPs) are one of the most widely used NPs. Their adverse effects on
either the host or its gut microbiota (GM) have been examined. Nevertheless, whether the …

Glioblastoma multiforme is the most aggressive brain tumor, and human T98G cells
constitute a useful glioblastoma multiforme model to evaluate the chemotherapeutic agents …

Tumors of the nervous system including glioblastoma multiforme (GBM) are the most
frequent and aggressive form of brain tumors; however, little is known about the impact of …

Involved in triglyceride (TG) and glycerophospholipid metabolism, the liver plays a crucial
physiological role in the human body both as a major metabolic integrator and a central hub …

Even in immortalized cell lines, circadian clocks regulate physiological processes in a time-
dependent manner, driving transcriptional and metabolic rhythms, the latter being able to …

Background: Metabolic abnormalities have long been predicted in Huntington's disease
(HD) but remain poorly characterized. Chronobiological dysregulation has been described …

Certain workplaces, like deep-sea voyages, subject workers to chronic psychological stress
and circadian rhythm disorders due to confined environments and frequent shifts. In this …