Allergic rhinitis (AR) poses a global health problem and can be challenging to treat. Many of
the current symptomatic treatments for AR have been available for decades, yet there has …

Nasal cytology is an easy, cheap, non‐invasive and point‐of‐care method to assess nasal
inflammation and disease‐specific cellular features. By means of nasal cytology, it is …

In a review of rupatadine published in 2008, the primary focus was on its role as an
antihistamine, with a thorough evaluation of its pharmacology and interaction with histamine …

Rupatadine is a modern non-sedating H1-antihistamine that also haswith additional
antagonist effects on platelet-activating factor (PAF). Under the tradenames Rupafin® and …

Introduction As a substrate of P-glycoprotein, levocetirizine should not cause sedative
effects. However, while cetirizine, a mixture of levocetirizine and dextrocetirizine, can slightly …

Background: Allergic rhinitis is characterized by a chronic inflammation of nasal mucosa and
represents a risk factor for asthma occurrence. H1 antihistamines reduce the symptoms of …

Introduction: Rupatadine is a second-generation H1-antihistamine with dual affinity for
histamine H1 and PAF receptors. Rupatadine is indicated for the treatment of allergic rhinitis …

Background Allergic rhinitis (AR) is the most common chronic allergic disease in school-age
children. An increased prevalence of attention deficit hyperactivity disorder (ADHD) in AR …

Background Urticaria is a distressing condition associated with diverse clinical
presentations. Chronic spontaneous urticaria (CsU) is characterized by wheals and …

Eosinophils are important effector cells involved in allergic inflammation. When stimulated,
eosinophils release a variety of mediators initiating, propagating, and maintaining local …