Antimalarial drug resistance in Africa: the calm before the storm?
MD Conrad, PJ Rosenthal - The Lancet Infectious Diseases, 2019 - thelancet.com
Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
Antimalarial drug resistance and implications for the WHO global technical strategy
Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …
Overall, anti-malarial, and non-malarial effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on birthweight: a mediation …
ME Roh, FO Ter Kuile, F Rerolle… - The Lancet Global …, 2020 - thelancet.com
Background Trials of intermittent preventive treatment (IPTp) of malaria in pregnant women
that compared dihydroartemisinin-piperaquine with the standard of care, sulfadoxine …
that compared dihydroartemisinin-piperaquine with the standard of care, sulfadoxine …
Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites
R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …
Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda
B Balikagala, M Sakurai-Yatsushiro, SI Tachibana… - Malaria journal, 2020 - Springer
Background Usage of chloroquine was discontinued from the treatment of Plasmodium
falciparum infection in almost all endemic regions because of global spread of resistant …
falciparum infection in almost all endemic regions because of global spread of resistant …
A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates …
Background Malaria is a major public health issue with substantial risks among vulnerable
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …
[HTML][HTML] School-aged children based seasonal malaria chemoprevention using artesunate-amodiaquine in Mali
MA Thera, AK Kone, B Tangara, E Diarra… - Parasite epidemiology …, 2018 - Elsevier
Introduction Malaria is still a public health problem in Africa. Seasonal Malaria
Chemoprevention (SMC) is an efficient control strategy recommended by WHO that targets …
Chemoprevention (SMC) is an efficient control strategy recommended by WHO that targets …
Piperaquine-induced QTc prolongation decreases with repeated monthly dihydroartemisinin-piperaquine dosing in pregnant Ugandan women
E Hughes, E Wallender, R Kajubi… - Clinical Infectious …, 2022 - academic.oup.com
Background Intermittent preventive treatment with monthly dihydroartemisinin-piperaquine
(DHA-PQ) is highly effective at preventing both malaria during pregnancy and placental …
(DHA-PQ) is highly effective at preventing both malaria during pregnancy and placental …
How has mass drug administration with dihydroartemisinin-piperaquine impacted molecular markers of drug resistance? A systematic review
Abstract The World Health Organization (WHO) recommends surveillance of molecular
markers of resistance to anti-malarial drugs. This is particularly important in the case of mass …
markers of resistance to anti-malarial drugs. This is particularly important in the case of mass …
Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children
Intermittent preventive treatment (IPT) with dihydroartemisinin-piperaquine (DP) is highly
protective against malaria in children, but is not standard in malaria-endemic countries …
protective against malaria in children, but is not standard in malaria-endemic countries …