Antibacterial coatings are rapidly emerging as a primary component of the global mitigation
strategy of bacterial pathogens. Thanks to recent concurrent advances in materials science …

The use of implantable medical devices is a common and indispensable part of medical
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …

Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in
various physiological as well as pathological processes. Over past decades, NO has …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

When blood first encounters the artificial surface of a medical device, a complex series of
biochemical reactions is triggered, potentially resulting in clinical complications such as …

The manner in which a mutually acceptable co-existence of biomaterials and tissues is
developed and sustained has been the focus of attention in biomaterials science for many …

Impaired diabetic wounds are serious pathophysiological complications associated with
persistent microbial infections including failure in the closure of wounds, and the cause of a …

Despite sterilization and aseptic procedures, bacterial infection remains a major impediment
to the utility of medical implants including catheters, artificial prosthetics, and subcutaneous …

The roles of nitric oxide (NO) in physiology and pathophysiology merit the use of NO as a
therapeutic for certain biomedical applications. Unfortunately, limited NO payloads, too rapid …

Despite considerable research and development efforts, the problem of infections related to
biomedical devices and implants persists. Bacteria evidently can readily colonize surfaces of …