Immune treatments for alcohol use disorder: A translational framework
While the immune system is essential for survival, an excessive or prolonged inflammatory
response, such as that resulting from sustained heavy alcohol use, can damage the host …
response, such as that resulting from sustained heavy alcohol use, can damage the host …
[HTML][HTML] Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis
Q Li, O Wang, B Ji, L Zhao, L Zhao - Nutrients, 2023 - mdpi.com
According to data from the World Health Organization, there were about 3 million deaths
caused by alcohol consumption worldwide in 2016, of which about 50% were related to liver …
caused by alcohol consumption worldwide in 2016, of which about 50% were related to liver …
[PDF][PDF] Mitochondrial double‐stranded RNA in exosome promotes Interleukin‐17 production through toll‐like receptor 3 in alcohol‐associated liver injury
Background and Aims Mitochondrial double‐stranded RNA (mtdsRNA) and its innate
immune responses have been reported previously; however, mtdsRNA generation and its …
immune responses have been reported previously; however, mtdsRNA generation and its …
Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination
D Zhang, X Li, Y Hu, H Jiang, Y Wu, Y Ding, K Yu… - Biochemical …, 2018 - Elsevier
Sepsis caused by Gram-negative bacteria is one of major causes for the progression of
acute lung injury (ALI) with limited treatment and effective medicines. Tabersonine is an …
acute lung injury (ALI) with limited treatment and effective medicines. Tabersonine is an …
[HTML][HTML] Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex
JR Ureña-Peralta, S Alfonso-Loeches… - Scientific reports, 2018 - nature.com
Alcohol abuse can induce brain injury and neurodegeneration, and recent evidence shows
the participation of immune receptors toll-like in the neuroinflammation and brain damage …
the participation of immune receptors toll-like in the neuroinflammation and brain damage …
Prenatal and adolescent alcohol exposure programs immunity across the lifespan: CNS-mediated regulation
For many individuals, first exposure to alcohol occurs either prenatally due to maternal
drinking, or during adolescence, when alcohol consumption is most likely to be initiated …
drinking, or during adolescence, when alcohol consumption is most likely to be initiated …
[HTML][HTML] Thrombospondin 2/toll-like receptor 4 axis contributes to HIF-1α-derived glycolysis in colorectal cancer
C Xu, L Gu, M Kuerbanjiang, S Wen, Q Xu… - Frontiers in …, 2020 - frontiersin.org
Background Aerobic glycolysis is a typical metabolic reprogramming in tumor cells, which
contributes to the survival and proliferation of tumor cells. The underlying mechanisms …
contributes to the survival and proliferation of tumor cells. The underlying mechanisms …
[HTML][HTML] Blood and brain gene expression signatures of chronic intermittent ethanol consumption in mice
LB Ferguson, AJ Roberts, RD Mayfield… - PLoS Computational …, 2022 - journals.plos.org
Alcohol Use Disorder (AUD) is a chronic, relapsing syndrome diagnosed by a
heterogeneous set of behavioral signs and symptoms. There are no laboratory tests that …
heterogeneous set of behavioral signs and symptoms. There are no laboratory tests that …
Protostemonine alleviates heat-killed methicillin-resistant Staphylococcus aureus-induced acute lung injury through MAPK and NF-κB signaling pathways
Y Wu, Y Nie, J Huang, Y Qiu, B Wan, G Liu… - International …, 2019 - Elsevier
Acute lung injury (ALI) and its most severe form acute respiratory distress syndrome (ARDS)
caused by gram-positive bacteria threatens human life because effective treatments and …
caused by gram-positive bacteria threatens human life because effective treatments and …
[PDF][PDF] Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis
P Stärkel, B Schnabl, S Leclercq… - Hepatology …, 2019 - Wiley Online Library
Mechanisms underlying alcohol‐induced liver injury and its progression still remain
incompletely understood. Animal models can only address some aspects of the …
incompletely understood. Animal models can only address some aspects of the …