Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
The evolution of commercial drug delivery technologies
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention
A Sharma, I Ahmad Farouk, SK Lal - Viruses, 2021 - mdpi.com
Three major outbreaks of the coronavirus, a zoonotic virus known to cause respiratory
disease, have been reported since 2002, including SARS-CoV, MERS-CoV and the most …
disease, have been reported since 2002, including SARS-CoV, MERS-CoV and the most …
COVID-19 transmission, current treatment, and future therapeutic strategies
VS Salian, JA Wright, PT Vedell, S Nair… - Molecular …, 2021 - ACS Publications
At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …
The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation
Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …
[HTML][HTML] Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
[HTML][HTML] Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy
Abstract In Italy, 128,948 confirmed cases and 15,887 deaths of people who tested positive
for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 …
for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 …
Cardiovascular considerations for patients, health care workers, and health systems during the COVID-19 pandemic
Abstract The coronavirus disease 2019 (COVID-19) is an infectious disease caused by
severe acute respiratory syndrome coronavirus 2 that has significant implications for the …
severe acute respiratory syndrome coronavirus 2 that has significant implications for the …
The SARS-CoV-2 spike glycoprotein biosynthesis, structure, function, and antigenicity: implications for the design of spike-based vaccine immunogens
L Duan, Q Zheng, H Zhang, Y Niu, Y Lou… - Frontiers in …, 2020 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …