[HTML][HTML] Proteomes are of proteoforms: embracing the complexity
K Carbonara, M Andonovski, JR Coorssen - Proteomes, 2021 - mdpi.com
Proteomes are complex—much more so than genomes or transcriptomes. Thus, simplifying
their analysis does not simplify the issue. Proteomes are of proteoforms, not canonical …
their analysis does not simplify the issue. Proteomes are of proteoforms, not canonical …
ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies
Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …
acquisition technique, quantification tool and processing method has emerged as the …
Identification of the gene signature reflecting schizophrenia's etiology by constructing artificial intelligence‐based method of enhanced reproducibility
Aims As one of the most fundamental questions in modern science,“what causes
schizophrenia (SZ)” remains a profound mystery due to the absence of objective gene …
schizophrenia (SZ)” remains a profound mystery due to the absence of objective gene …
A critical assessment of the feature selection methods used for biomarker discovery in current metaproteomics studies
Microbial community (MC) has great impact on mediating complex disease indications,
biogeochemical cycling and agricultural productivities, which makes metaproteomics …
biogeochemical cycling and agricultural productivities, which makes metaproteomics …
Biomarker discovery for immunotherapy of pituitary adenomas: enhanced robustness and prediction ability by modern computational tools
Pituitary adenoma (PA) is prevalent in the general population. Due to its severe
complications and aggressive infiltration into the surrounding brain structure, the effective …
complications and aggressive infiltration into the surrounding brain structure, the effective …
Assessing the effectiveness of direct data merging strategy in long-term and large-scale pharmacometabonomics
Because of the extended period of clinic data collection and huge size of analyzed samples,
the long-term and large-scale pharmacometabonomics profiling is frequently encountered in …
the long-term and large-scale pharmacometabonomics profiling is frequently encountered in …
Identification of key long non-coding RNAs in the pathology of Alzheimer's disease and their functions based on genome-wide associations study, microarray, and …
The pathogenesis of Alzheimer's disease (AD) is identified to be significantly regulated by
long non-coding RNA (lncRNA) based on in vivo and clinical experiments. Single nucleotide …
long non-coding RNA (lncRNA) based on in vivo and clinical experiments. Single nucleotide …
Identifying potential mitochondrial proteome signatures associated with the pathogenesis of pulmonary arterial hypertension in the rat model
J Wang, MN Uddin, Q Li, A Aierken… - Oxidative Medicine …, 2022 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a severe and progressive disease that affects the
heart and lungs and a global health concern that impacts individuals and society. Studies …
heart and lungs and a global health concern that impacts individuals and society. Studies …
Computational perspective on the current state of the methods and new challenges in cancer drug discovery
Computational Perspective on the Current State of the Methods and New Challenges in Cancer
Drug Discovery Computational Perspective on the Current State of the Methods and New …
Drug Discovery Computational Perspective on the Current State of the Methods and New …
[HTML][HTML] Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B
J Li, J Yang, L Hua, R Wang, H Li, C Zhang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Epithelium-specific Ets protein 3 (Ese-3), a member of the Ets family of transcription
factors, plays an important role in the development of cancers. However, little is known …
factors, plays an important role in the development of cancers. However, little is known …