Diabetes associated with male reproductive system damages: Onset of presentation, pathophysiological mechanisms and drug intervention

GJ Shi, ZM Li, J Zheng, J Chen, XX Han, J Wu… - Biomedicine & …, 2017 - Elsevier
Diabetes mellitus (DM) is a major health problem that affects patients' quality of life quality
throughout the world due to its many complications. Reproductive dysfunction is one of the …

[HTML][HTML] Okra (Abelmoscus esculentus) improved islets structure, and down-regulated PPARs gene expression in pancreas of high-fat diet and streptozotocin-induced …

NE Majd, MR Tabandeh, A Shahriari… - Cell Journal …, 2018 - ncbi.nlm.nih.gov
Objective Okra (Abelmoschus esculentus) is a tropical vegetable that is rich in
carbohydrates, fibers, proteins and natural antioxidants. The aim of the present study was to …

Protective effects of sodium nitrate against testicular apoptosis and spermatogenesis impairments in streptozotocin-induced diabetic male rats

R Keyhanmanesh, G Hamidian, MR Alipour, M Ranjbar… - Life sciences, 2018 - Elsevier
Aims As nitric oxide (NO) production is essential for insulin signaling, glucose uptake,
endothelial function, and regulation of apoptosis, the loss of bioavailable NO may be a …

[HTML][HTML] Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway

J Zhang, X Zhang, Y Liu, Z Su, FU Dawar, H Dan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Amino acid supplementation is an efficient and effective strategy to increase sperm quality.
In our research, a comparative study was conducted to screen free amino acids to improve …

[HTML][HTML] Troxerutin affects the male fertility in prepubertal type 1 diabetic male rats

ZZ Oskuye, FM Bavil, GR Hamidian… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Troxerutin affects the male fertility in prepubertal type 1 diabetic male rats - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Antioxidant, anti-inflammatory, and anti-apoptotic effects of zinc supplementation in testes of rats with experimentally induced diabetes

NM Aziz, MY Kamel, MS Mohamed… - Applied Physiology …, 2018 - cdnsciencepub.com
One of the major obstacles that males with diabetes may confront is subfertility or infertility.
Thus, the present study investigated the effect of co-administration of metformin and zinc …

Two months sodium nitrate supplementation alleviates testicular injury in streptozotocin‐induced diabetic male rats

H Oghbaei, MR Alipour, G Hamidian… - Experimental …, 2018 - Wiley Online Library
New Findings What is the central question of this study? Can low‐dose inorganic nitrate
supplementation prevent testicular structural and functional alterations in streptozotocin …

A comparative study between curcumin and curcumin nanoemulsion on high-fat, high-fructose diet-induced impaired spermatogenesis in rats

M Nasr, H Abd-Allah, OAH Ahmed-Farid… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Curcumin is a promising nutraceutical with reported diverse therapeutic
properties, but of limited oral bioavailability. The current manuscript investigates the role of …

The effect of prolonged dietary sodium nitrate treatment on the hypothalamus-pituitary-gonadal axis and testicular structure and function in streptozotocin-induced …

H Oghbaei, G Hamidian, MR Alipour, S Alipour… - Food & function, 2020 - pubs.rsc.org
The aim of this study was to evaluate the effect of prolonged dietary nitrate supplementation
on the gonadotropin level, testicular histology and morphometry, expression of miR-34b and …

Effects of dietary L-leucine supplementation on testicular development and semen quality in boars

Y Lin, J Li, K Wang, Z Fang, L Che, S Xu… - Frontiers in Veterinary …, 2022 - frontiersin.org
Sperm and seminal plasma are rich in leucine, and leucine can promote the protein
synthesis. This property makes it an interesting amino acid to increase sperm quality of …