MS‐based glycomics and glycoproteomics methods enabling isomeric characterization
Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …
Advances in mass spectrometry‐based glycomics—An update covering the period 2017–2021
The wide variety of chemical properties and biological functions found in proteins is attained
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
Coupling isotopic shifts with collision cross-section measurements for carbohydrate characterization in high-resolution ion mobility separations
DL Williamson, G Nagy - Analytical chemistry, 2023 - ACS Publications
Herein, we introduce a two-dimensional strategy to better characterize carbohydrate
isomers. In a single experiment, we can derive cyclic ion mobility-mass spectrometry (cIMS …
isomers. In a single experiment, we can derive cyclic ion mobility-mass spectrometry (cIMS …
Liquid chromatography and capillary electrophoresis in glycomic and glycoproteomic analysis
K Molnarova, K Cokrtova, A Tomnikova… - Monatshefte für Chemie …, 2022 - Springer
Glycosylation is one of the most significant and abundant post-translational modifications in
cells. Glycomic and glycoproteomic analyses involve the characterization of …
cells. Glycomic and glycoproteomic analyses involve the characterization of …
State‐of‐the‐art glycosaminoglycan characterization
A Zappe, RL Miller, WB Struwe… - Mass Spectrometry …, 2022 - Wiley Online Library
Glycosaminoglycans (GAGs) are heterogeneous acidic polysaccharides involved in a range
of biological functions. They have a significant influence on the regulation of cellular …
of biological functions. They have a significant influence on the regulation of cellular …
Targeted N-Glycan Analysis with Parallel Reaction Monitoring Using a Quadrupole-Orbitrap Hybrid Mass Spectrometer
Targeted mass spectrometric analysis is widely employed across various omics fields. The
approach has been successfully employed for the structural analysis of proteins, glycans …
approach has been successfully employed for the structural analysis of proteins, glycans …
MS-based glycomics: An analytical tool to assess nervous system diseases
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …
increasing due to the globe's aging population. Such diseases affect the nervous system …
Using micro pillar array columns (μPAC) for the analysis of permethylated glycans
Glycosylation is a complex and common post-translational modification of proteins. To study
glycosylation, liquid chromatography-mass spectrometry (LC-MS) is often used to profile and …
glycosylation, liquid chromatography-mass spectrometry (LC-MS) is often used to profile and …
Salmonella enterica serovar Typhimurium chitinases modulate the intestinal glycome and promote small intestinal invasion
Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the leading causes of
food-borne illnesses worldwide. To colonize the gastrointestinal tract, S. Typhimurium …
food-borne illnesses worldwide. To colonize the gastrointestinal tract, S. Typhimurium …
Direct Comparison of N-Glycans and Their Isomers Derived from Spike Glycoprotein 1 of MERS-CoV, SARS-CoV-1, and SARS-CoV-2
The emergence of COVID-19 pandemic has engaged the scientific community around the
globe in the rapid development of effective therapeutics and vaccines. Owing to its crucial …
globe in the rapid development of effective therapeutics and vaccines. Owing to its crucial …