Surgical management of colorectal cancer liver metastases

C Padmanabhan, DP Nussbaum… - Surgical Oncology …, 2021 - surgonc.theclinics.com
Colorectal cancer is the second most common cancer diagnosis in women and the third
most common cancer diagnosis in men worldwide. 1 Approximately 1.8 million cases of …

Oxaliplatin-based intra-arterial chemotherapy in colo-rectal cancer liver metastases: a review from pharmacology to clinical application

G Ranieri, M Laforgia, P Nardulli, S Ferraiuolo… - Cancers, 2019 - mdpi.com
Liver metastases (LM) are often consequences of colo-rectal cancer (CRC) and the majority
of patients have unresectable LM. Oxaliplatin-based intravenous chemotherapy represents …

Comparative effectiveness of hepatic artery based therapies for unresectable colorectal liver metastases: a meta-analysis

AJ Zacharias, TT Jayakrishnan, R Rajeev, WS Rilling… - PloS one, 2015 - journals.plos.org
Background Patients with unresectable Colorectal Liver Metastases (CRLM) are
increasingly being managed using Hepatic Artery Based Therapies (HAT), including Hepatic …

Hepatic arterial infusion in combination with systemic chemotherapy in patients with hepatic metastasis from colorectal cancer: a randomized phase II study …

JS Kim, H Kim, SY Lee, YD Han, K Han, BS Min… - BMC cancer, 2023 - Springer
Background Although 80% of patients with metastatic colorectal cancer (CRC) experience
liver metastases, only 10–25% undergo resection at the time of diagnosis. Even in initially …

[HTML][HTML] Hepatic arterial infusion of oxaliplatin plus systemic chemotherapy and targeted therapy for unresectable colorectal liver metastases

A Boilève, A De Cuyper, A Larive, L Mahjoubi… - European Journal of …, 2020 - Elsevier
Background Hepatic arterial infusion (HAI) combined with systemic chemotherapy has
shown promising results in patients with unresectable colorectal liver metastases (CRLM) …

Systematic review and meta-analysis of hepatic arterial infusion chemotherapy as bridging therapy for colorectal liver metastases

DL Chan, NA Alzahrani, DL Morris, TC Chua - Surgical Oncology, 2015 - Elsevier
Background Hepatic arterial infusion chemotherapy (HAIC) has been shown to be beneficial
in the management of unresectable colorectal liver metastases (CRLM). This systematic …

A randomized phase II trial of hepatic arterial infusion of oxaliplatin plus raltitrexed versus oxaliplatin plus 5-fluorouracil for unresectable colorectal cancer liver …

AW Feng, JH Guo, S Gao, FX Kou, SX Liu, P Liu… - Frontiers in …, 2022 - frontiersin.org
Background The purpose was to compare the efficacy and safety of hepatic arterial infusion
(HAI) of oxaliplatin plus raltitrexed (TOMOX) to those of oxaliplatin plus 5-fluorouracil …

5-fluorouracil treatment alters the efficiency of translational recoding

J Ge, J Karijolich, Y Zhai, J Zheng, YT Yu - Genes, 2017 - mdpi.com
5-fluorouracil (5-FU) is a chemotherapeutic agent that has been extensively studied since its
initial development in the 1950s. It has been suggested that the mechanism of action of 5-FU …

Outcomes of a phase I/II trial of hepatic arterial infusion of oxaliplatin combined with intravenous 5-fluorouracil and l-leucovorin in patients with unresectable liver …

Y Sato, Y Inaba, T Ura, H Nishiofuku… - Journal of …, 2018 - Springer
Purpose The purpose of this study was to assess hepatic arterial infusion (HAI) of oxaliplatin
combined with intravenous 5-fluorouracil (5-FU) and l-leucovorin (l-LV) in colorectal cancer …

A phase I clinical trial of hepatic arterial infusion of oxaliplatin and oral capecitabine, with or without intravenous bevacizumab, in patients with advanced cancer and …

E Fountzilas, E Krishnan, F Janku, S Fu… - Cancer chemotherapy …, 2018 - Springer
Background We investigated hepatic arterial infusion (HAI) oxaliplatin combined with
capecitabine+/− bevacizumab in advanced cancer with predominant liver involvement …