Dual hypoxia-responsive supramolecular complex for cancer target therapy

JS Guo, JJ Li, ZH Wang, Y Liu, YX Yue, HB Li… - Nature …, 2023 - nature.com
The prognosis with pancreatic cancer is among the poorest of any human cancer. One of the
important factors is the tumor hypoxia. Targeting tumor hypoxia is considered a desirable …

Recent Advances in C(sp3)–C(sp3) Cross-Coupling Chemistry: A Dominant Performance of Nickel Catalysts

R Kranthikumar - Organometallics, 2022 - ACS Publications
The formation of a new C–C bond at sp3-hybridized centers is highly desirable, as it opens
up a unique, unexplored chemical space. The revolutionary discoveries in this field meet the …

Julia‐Kocienski Olefination in the Synthesis of Trisubstituted Alkenes: Recent Progress

KA Ouzounthanasis, SR Rizos… - European Journal of …, 2023 - Wiley Online Library
Julia‐Kocienski olefination, a coupling reaction between a carbonyl component and a
sulfone partner, has emerged as a powerful synthetic tool in the preparation of several …

Total synthesis and stereochemical assignment of rakicidin F

F Han, G Liu, X Zhao, S Du, Y Ding, Q Zhang… - Organic & …, 2022 - pubs.rsc.org
Total synthesis of rakicidin F was accomplished in 20 linear steps (0.68% overall yield),
which enabled the configural determination of its six stereogenic centers as 2R, 15R, 16R …