Critical review of exposure and effects: implications for setting regulatory health criteria for ingested copper
AA Taylor, JS Tsuji, MR Garry, ME McArdle… - Environmental …, 2020 - Springer
Decades of study indicate that copper oral exposures are typically not a human health
concern. Ingesting high levels of soluble copper salts can cause acute gastrointestinal …
concern. Ingesting high levels of soluble copper salts can cause acute gastrointestinal …
Copper dyshomeostasis in neurodegenerative diseases—therapeutic implications
G Gromadzka, B Tarnacka, A Flaga… - International journal of …, 2020 - mdpi.com
Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …
Hypoxia, oxidative stress, and inflammation: three faces of neurodegenerative diseases
A Merelli, M Repetto, A Lazarowski… - Journal of Alzheimer's …, 2021 - content.iospress.com
The cerebral hypoxia-ischemia can induce a wide spectrum of biologic responses that
include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and …
include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and …
Naturally occurring antioxidant therapy in Alzheimer's disease
AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …
2040. Although currently available treatments help with symptom management, they do not …
Current biomedical use of copper chelation therapy
S Baldari, G Di Rocco, G Toietta - International journal of molecular …, 2020 - mdpi.com
Copper is an essential microelement that plays an important role in a wide variety of
biological processes. Copper concentration has to be finely regulated, as any imbalance in …
biological processes. Copper concentration has to be finely regulated, as any imbalance in …
Copper toxicity links to pathogenesis of Alzheimer's disease and therapeutics approaches
HW Ejaz, W Wang, M Lang - International Journal of Molecular Sciences, 2020 - mdpi.com
Alzheimer's disease (AD) is an irreversible, age-related progressive neurological disorder,
and the most common type of dementia in aged people. Neuropathological lesions of AD …
and the most common type of dementia in aged people. Neuropathological lesions of AD …
Copper coordination compounds as biologically active agents
O Krasnovskaya, A Naumov, D Guk, P Gorelkin… - International Journal of …, 2020 - mdpi.com
Copper-containing coordination compounds attract wide attention due to the redox activity
and biogenicity of copper ions, providing multiple pathways of biological activity. The …
and biogenicity of copper ions, providing multiple pathways of biological activity. The …
Prussian blue nanoparticles: synthesis, surface modification, and biomedical applications
MA Busquets, J Estelrich - Drug Discovery Today, 2020 - Elsevier
Highlights•Prussian blue nanoparticles are a multifunctional platform for theranostics.•The
porous structure of nanoparticles allows the capture of cations.•The absorption of NIR …
porous structure of nanoparticles allows the capture of cations.•The absorption of NIR …
Polyphenols as potential metal chelation compounds against Alzheimer's disease
J Lakey-Beitia, AM Burillo, G La Penna… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …
Copper, iron, and manganese toxicity in neuropsychiatric conditions
B Tarnacka, A Jopowicz, M Maślińska - International journal of molecular …, 2021 - mdpi.com
Copper, manganese, and iron are vital elements required for the appropriate development
and the general preservation of good health. Additionally, these essential metals play key …
and the general preservation of good health. Additionally, these essential metals play key …