A global perspective on H9N2 avian influenza virus

TP Peacock, J James, JE Sealy, M Iqbal - Viruses, 2019 - mdpi.com
H9N2 avian influenza viruses have become globally widespread in poultry over the last two
decades and represent a genuine threat both to the global poultry industry but also humans …

SARS-CoV-2 one year on: evidence for ongoing viral adaptation

TP Peacock, R Penrice-Randal… - Journal of General …, 2021 - microbiologyresearch.org
SARS-CoV-2 is thought to have originated in the human population from a zoonotic spillover
event. Infection in humans results in a variety of outcomes ranging from asymptomatic cases …

H9 influenza viruses: an emerging challenge

S Carnaccini, DR Perez - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Influenza A viruses (IAVs) of the H9 subtype are enzootic in Asia, the Middle East, and parts
of North and Central Africa, where they cause significant economic losses to the poultry …

The emergence of new antigen branches of H9N2 avian influenza virus in China due to antigenic drift on hemagglutinin through antibody escape at immunodominant …

N Zhang, K Quan, Z Chen, Q Hu, M Nie… - Emerging microbes & …, 2023 - Taylor & Francis
Vaccination is a crucial prevention and control measure against H9N2 avian influenza
viruses (AIVs) that threaten poultry production and public health. However, H9N2 AIVs in …

Status and challenges for vaccination against avian H9N2 influenza virus in China

J Dong, Y Zhou, J Pu, L Liu - Life, 2022 - mdpi.com
In China, H9N2 avian influenza virus (AIV) has become widely prevalent in poultry, causing
huge economic losses after secondary infection with other pathogens. Importantly, H9N2 …

HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus

R Zhu, S Xu, W Sun, Q Li, S Wang, H Shi, X Liu - Veterinary research, 2022 - Springer
Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the
H9N2 avian influenza virus (H9N2 virus) has been clustered into multiple lineages, and its …

Antigenic evolution characteristics and immunological evaluation of H9N2 avian influenza viruses from 1994–2019 in China

Q Liu, L Zhao, Y Guo, Y Zhao, Y Li, N Chen, Y Lu, M Yu… - Viruses, 2022 - mdpi.com
The H9N2 subtype avian influenza viruses (AIVs) have been circulating in China for more
than 20 years, attracting more and more attention due to the potential threat of them. At …

Genetic determinants of receptor-binding preference and zoonotic potential of H9N2 avian influenza viruses

TP Peacock, JE Sealy, WT Harvey, DJ Benton… - Journal of …, 2021 - Am Soc Microbiol
Receptor recognition and binding is the first step of viral infection and a key determinant of
host specificity. The inability of avian influenza viruses to effectively bind human-like …

The molecular determinants of antigenic drift in a novel avian influenza A (H9N2) variant virus

Y Zheng, Y Guo, Y Li, B Liang, X Sun, S Li, H Xia… - Virology Journal, 2022 - Springer
Background In early 2020, a novel H9N2 AIV immune escape variant emerged in South
China and rapidly spread throughout mainland China. The effectiveness of the current H9N2 …

Antigenic and molecular characterization of low pathogenic avian influenza A (H9N2) viruses in sub-Saharan Africa from 2017 through 2019

M Fusade-Boyer, F Djegui, K Batawui… - Emerging microbes & …, 2021 - Taylor & Francis
ABSTRACT Sub-Saharan Africa was historically considered an animal influenza cold spot,
with only sporadic highly pathogenic H5 outbreaks detected over the last 20 years …