Viscoelastic microfluidics: Progress and challenges

J Zhou, I Papautsky - Microsystems & Nanoengineering, 2020 - nature.com
The manipulation of cells and particles suspended in viscoelastic fluids in microchannels
has drawn increasing attention, in part due to the ability for single-stream three-dimensional …

Fundamentals and applications of inertial microfluidics: A review

J Zhang, S Yan, D Yuan, G Alici, NT Nguyen… - Lab on a Chip, 2016 - pubs.rsc.org
In the last decade, inertial microfluidics has attracted significant attention and a wide variety
of channel designs that focus, concentrate and separate particles and fluids have been …

Point of care testing for infectious diseases

H Chen, K Liu, Z Li, P Wang - Clinica chimica acta, 2019 - Elsevier
Infectious diseases are caused by pathogenic microorganisms and can be transmitted
between individuals and populations thus threatening the general public health and …

A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Isolation and retrieval of circulating tumor cells using centrifugal forces

HW Hou, ME Warkiani, BL Khoo, ZR Li, RA Soo… - Scientific reports, 2013 - nature.com
Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer
patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral …

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

SM Davidson, O Jonas, MA Keibler, HW Hou… - Nature medicine, 2017 - nature.com
Mammalian tissues rely on a variety of nutrients to support their physiological functions. It is
known that altered metabolism is involved in the pathogenesis of cancer, but which nutrients …

Advancements in microfluidics for nanoparticle separation

T Salafi, KK Zeming, Y Zhang - Lab on a Chip, 2017 - pubs.rsc.org
Nanoparticles have been widely implemented for healthcare and nanoscience industrial
applications. Thus, efficient and effective nanoparticle separation methods are essential for …

Deformability-based cell classification and enrichment using inertial microfluidics

SC Hur, NK Henderson-MacLennan, ERB McCabe… - Lab on a Chip, 2011 - pubs.rsc.org
The ability to detect and isolate rare target cells from heterogeneous samples is in high
demand in cell biology research, immunology, tissue engineering and medicine …

Blood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications

SO Catarino, RO Rodrigues, D Pinho, JM Miranda… - Micromachines, 2019 - mdpi.com
Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …

Continuous flow microfluidic separation and processing of rare cells and bioparticles found in blood–A review

M Antfolk, T Laurell - Analytica chimica acta, 2017 - Elsevier
Rare cells in blood, such as circulating tumor cells or fetal cells in the maternal circulation,
posses a great prognostic or diagnostic value, or for the development of personalized …