Ecology, evolution and spillover of coronaviruses from bats

M Ruiz-Aravena, C McKee, A Gamble, T Lunn… - Nature Reviews …, 2022 - nature.com
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

T Tang, M Bidon, JA Jaimes, GR Whittaker, S Daniel - Antiviral research, 2020 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has focused attention on the
need to develop effective therapies against the causative agent, SARS-CoV-2, and also …

From SARS to MERS, thrusting coronaviruses into the spotlight

Z Song, Y Xu, L Bao, L Zhang, P Yu, Y Qu, H Zhu… - viruses, 2019 - mdpi.com
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …

[HTML][HTML] Origin and evolution of pathogenic coronaviruses

J Cui, F Li, ZL Shi - Nature reviews microbiology, 2019 - nature.com
Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory
syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses …

[HTML][HTML] Molecular immune pathogenesis and diagnosis of COVID-19

X Li, M Geng, Y Peng, L Meng, S Lu - Journal of pharmaceutical analysis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of …

Structural insights into coronavirus entry

MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …

Animal and translational models of SARS-CoV-2 infection and COVID-19

MD Johansen, A Irving, X Montagutelli, MD Tate… - Mucosal …, 2020 - nature.com
COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical
community is in a race to define and develop effective preventions and treatments. The …

Global epidemiology of bat coronaviruses

ACP Wong, X Li, SKP Lau, PCY Woo - Viruses, 2019 - mdpi.com
Bats are a unique group of mammals of the order Chiroptera. They are highly diversified and
are the group of mammals with the second largest number of species. Such highly …

Structure, function, and evolution of coronavirus spike proteins

F Li - Annual review of virology, 2016 - annualreviews.org
The coronavirus spike protein is a multifunctional molecular machine that mediates
coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its …