Surgery is the frontline treatment for a large number of cancers. The objective of these
excisional surgeries is the complete removal of the primary tumor with sufficient safety …

Optical imaging has become an indispensable technology in the clinic. The molecular
design of cell-targeted and highly sensitive materials, the validation of specific disease …

Purpose: Completeness of cytoreductive surgery is a key prognostic factor for survival in
patients with ovarian cancer. The ability to differentiate clearly between malignant and …

Background Tumour-targeted fluorescence imaging has the potential to advance current
practice of oncological surgery by selectively highlighting malignant tissue during surgery …

Background Near-infrared (NIR) fluorescence is a promising novel imaging technique that
can aid in intraoperative demarcation of pancreatic cancer (PDAC) and thus increase radical …

Intraoperative imaging with antibodies labeled with both a radionuclide for initial guidance
and a near-infrared dye for adequate tumor delineation may overcome the main limitation of …

Methods Two-to-three hours before surgery 0.1 mg/kg EC17 was intravenously administered
to 12 patients undergoing surgery for ovarian cancer and to 3 patients undergoing surgery …

Objective In ovarian cancer, two of the most important prognostic factors for survival are
completeness of staging and completeness of cytoreductive surgery. Therefore, intra …

Background Several studies demonstrated that intraoperative near-infrared fluorescence
(NIRF) imaging using indocyanine green (ICG) identifies (sub) capsular colorectal liver …

In vivo cancer margin delineation during surgery remains a major challenge. Despite the
availability of several image guidance techniques and intraoperative assessment, clear …