The effect of macromolecular crowding on mobility of biomolecules, association kinetics, and gene expression in living cells
M Tabaka, T Kalwarczyk, J Szymanski, S Hou… - Frontiers in …, 2014 - frontiersin.org
We discuss a quantitative influence of macromolecular crowding on biological processes:
motion, bimolecular reactions, and gene expression in prokaryotic and eukaryotic cells. We …
motion, bimolecular reactions, and gene expression in prokaryotic and eukaryotic cells. We …
Polymers at interfaces and the interactions in colloidal dispersions
A Vrij - Pure and Applied Chemistry, 1976 - degruyter.com
Solutions of different polymers in the same solvent are incompatible as a rule and show
phase separation when they are mixed. H incompatibility is also to be observed in systems …
phase separation when they are mixed. H incompatibility is also to be observed in systems …
Extracellular fluid viscosity enhances liver cancer cell mechanosensing and migration
The extracellular fluid (ECF) is a crowded environment containing macromolecules that
determine its characteristic density, osmotic pressure, and viscosity, which greatly differ …
determine its characteristic density, osmotic pressure, and viscosity, which greatly differ …
Crossover regime for the diffusion of nanoparticles in polyethylene glycol solutions: influence of the depletion layer
N Ziębacz, SA Wieczorek, T Kalwarczyk, M Fiałkowski… - Soft Matter, 2011 - pubs.rsc.org
The viscosity in soft matter systems is a scale dependent quantity. In polymer solutions the
viscosity of nanoprobes of size R approaches the macroscopic viscosity when R exceeds …
viscosity of nanoprobes of size R approaches the macroscopic viscosity when R exceeds …
Tuning the catalytic properties of P22 nanoreactors through compositional control
Enzymes are biomacromolecular protein catalysts that are widely used in a plethora of
industrial-scale applications due to their high selectivity, efficiency and ability to work under …
industrial-scale applications due to their high selectivity, efficiency and ability to work under …
Marangoni Droplets of Dextran in PEG Solution and Its Motile Change Due to Coil–Globule Transition of Coexisting DNA
T Furuki, H Sakuta, N Yanagisawa… - … Applied Materials & …, 2024 - ACS Publications
Motile droplets using Marangoni convection are attracting attention for their potential as cell-
mimicking small robots. However, the motion of droplets relative to the internal and external …
mimicking small robots. However, the motion of droplets relative to the internal and external …
Effect of crowding by Dextrans in enzymatic reactions
The interior of the living cell is highly concentrated and structured with molecules that have
different shapes and sizes. Almost all experimental biochemical data have been obtained …
different shapes and sizes. Almost all experimental biochemical data have been obtained …
Macromolecular Crowding Effect upon in Vitro Enzyme Kinetics: Mixed Activation–Diffusion Control of the Oxidation of NADH by Pyruvate Catalyzed by Lactate …
C Balcells, I Pastor, E Vilaseca… - The Journal of …, 2014 - ACS Publications
Enzyme kinetics studies have been usually designed as dilute solution experiments, which
differ substantially from in vivo conditions. However, cell cytosol is crowded with a high …
differ substantially from in vivo conditions. However, cell cytosol is crowded with a high …
TPE based aggregation induced emission fluorescent sensors for viscosity of liquid and mechanical properties of hydrogel
N Wang, H Yao, Q Tao, J Sun, H Ma, Y Wang… - Chinese Chemical …, 2022 - Elsevier
ABSTRACT Two amphiphilic TPE E/Z isomers with aggregation induced emission (AIE)
property have been synthesized and characterized. The logarithmic fluorescent intensity of …
property have been synthesized and characterized. The logarithmic fluorescent intensity of …
Small crowders slow down kinesin-1 stepping by hindering motor domain diffusion
The dimeric motor protein kinesin-1 moves processively along microtubules against forces
of up to 7 pN. However, the mechanism of force generation is still debated. Here, we point to …
of up to 7 pN. However, the mechanism of force generation is still debated. Here, we point to …