Saccharin (SAC) is an emerging contaminant, widely detected in the environment, with
potential ecotoxicity risks to aqueous organisms and human beings. Wastewater treatment …

Background and objectives: This study evaluated the effect of chronic consumption of
saccharin on important physiological and biochemical parameters in rats. Materials and …

The increase of obesity and its metabolic comorbidities have led to a growing consumption
of sugar-free products, where sucrose is replaced by low-calorie sweeteners. Since the …

Next‐generation gene and engineered‐cell therapies benefit from incorporating synthetic
gene networks that can precisely regulate the therapeutic output in response to externally …

Persistent and mobile chemicals (PMs) and per-and polyfluoroalkyl substances (PFAS) are
groups of chemicals that have received recent global attention due to their potential health …

High intensity-sweeteners (HIS) are natural or synthetic substances, sweeter than sugar,
providing sweetness without calories. Sweeteners are mainly used as an aid in losing …

Improving the stability, bioavailability, and processability of active pharmaceutical
ingredients (APIs) has been the key research goal in the field of pharmaceutical …

A Jahn-Teller distorted octahedral cobalt (II) complex with saccharin and water ligands was
synthesized and characterized using single-crystal X-ray diffraction, density functional theory …

Widespread use and the continuous increase in consumption has intensified the presence
of food additives and their metabolites in the environment. The growing awareness that …

Considering the vast use of sweeteners by the Brazilian population and the constant need
for toxicological studies of food additives, this study aimed to evaluate the cytotoxic and …