Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …

Stromal desmoplastic reaction in pancreatic ductal adenocarcinoma (PDAC) involves
significant accumulation of type I collagen (Col1). However, the precise molecular and …

This review aims to critically analyze the pathways of interaction and the pathogenic
mechanisms linking periodontitis and oral bacteria with the initiation/progression of cancer …

Background and Aims Because of a paucity of effective treatment options, metastasis is still
a major cause for HCC‐associated mortality. The molecular mechanism of inflammation …

Chemokines are chemotactic cytokines that mediate immune cell chemotaxis and lymphoid
tissue development. Recent advances have indicated that chemokines and their cognate …

Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Surgical resection remains the mainstay treatment for solid cancers, especially for localized
disease. However, the postoperative immunosuppression provides a window for cancer cell …

Tumor microenvironment (TME) formation is a major cause of immunosuppression. The TME
consists of a considerable number of macrophages and stromal cells that have been …

Distant metastasis is the main cause of death for cancer patients. Recently, the newly
discovered programmed cell death includes necroptosis, pyroptosis, and ferroptosis, which …