In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …

Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …

Curcumin (diferuloylmethane) is the main constituent extracted from turmeric. This
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …

Angiogenesis is the process by which blood vessels form from pre-existing vessels. It plays
a key role in many biological processes, including embryonic development and wound …

Metabolism is considered to be the core of all cellular activity. Thus, extensive studies of
metabolic processes are ongoing in various fields of biology, including cancer research …

Anti-angiogenic (AA) treatments have received significant research interest due to the key
role of angiogenesis in cancer progression. AA agents can have a strong effect on cancer …

Computational models are not just appealing because they can simulate and predict the
development of biological phenomena across multiple spatial and temporal scales, but also …

The effectiveness of chemotherapy in cancer cell regression is often limited by drug
resistance, toxicity, and neoplasia heterogeneity. However, due to the significant …

The future of personalised medicine lies in the development of increasingly sophisticated
digital twins, where the patient-specific data is fed into predictive computational models that …

This study numerically analyzes the fluid flow and solute transport in a solid tumor to
comprehensively examine the consequence of normalization induced by anti-angiogenic …