Systemic infections with pathogenic or facultative pathogenic bacteria are associated with
activation and aggregation of platelets leading to thrombocytopenia and activation of the …

Vaccination is a significant advancement or preventative strategy for controlling the spread
of various severe infectious and noninfectious diseases. The purpose of vaccination is to …

ABSTRACT Nontypeable Haemophilus influenzae (NTHi) causes respiratory infections that
lead to high morbidity and mortality worldwide, encouraging development of effective …

Streptococcus pneumoniae remains a significant global threat, with existing vaccines having
important limitations such as restricted serotype coverage and high manufacturing costs …

Introduction: Nasopharyngeal colonization is a precondition for mucosal and invasive
pneumococcal disease. Prevention of colonization may reduce pneumococcal transmission …

Introduction: The hydrophilic, polymeric chain of the lipoteichoic acid (LTA) of the Gram-
positive pathobiont Streptococcus pneumoniae is covalently linked to the …

Bacterial lipoproteins are structurally divided into two groups, based on their lipid moieties:
diacylated (present in Gram-positive bacteria) and triacylated (present in some Gram …

Toll-like receptor 2 (TLR2) signaling is a pivotal component of immune system activation,
and it is closely linked to the lipidation of bacterial proteins. This lipidation is guided by …

The polarization status of porcine alveolar macrophages (PAMs) determines the infectivity of
porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV infection skews …

Streptococcus pneumoniae colonizes asymptomatically the upper respiratory tract as a
commensal, but has also a high virulence potential and can leave this ecological niche …