RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
G-quadruplex-binding proteins: promising targets for drug design
H Shu, R Zhang, K Xiao, J Yang, X Sun - Biomolecules, 2022 - mdpi.com
G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with
the potential to form G4s are abundant in regulatory regions of the genome including …
the potential to form G4s are abundant in regulatory regions of the genome including …
Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar
J Kubíková, G Ubartaitė, J Metz… - Proceedings of the …, 2023 - National Acad Sciences
Drosophila Smaug and its orthologs comprise a family of mRNA repressor proteins that
exhibit various functions during animal development. Smaug proteins contain a …
exhibit various functions during animal development. Smaug proteins contain a …
RNA G-quadruplex in functional regulation of noncoding RNA: Challenges and emerging opportunities
VJ Sahayasheela, H Sugiyama - Cell Chemical Biology, 2024 - cell.com
Summary G-quadruplexes (G4s) are stable, noncanonical structures formed in guanine (G)-
rich sequences of DNA/RNA. G4 structures are reported to play a regulatory role in various …
rich sequences of DNA/RNA. G4 structures are reported to play a regulatory role in various …
RNA degradome analysis reveals DNE1 endoribonuclease is required for the turnover of diverse mRNA substrates in Arabidopsis
VK Nagarajan, CJ Stuart, AT DiBattista… - The Plant …, 2023 - academic.oup.com
In plants, cytoplasmic mRNA decay is critical for posttranscriptionally controlling gene
expression and for maintaining cellular RNA homeostasis. Arabidopsis DCP1-ASSOCIATED …
expression and for maintaining cellular RNA homeostasis. Arabidopsis DCP1-ASSOCIATED …
Impact of protein domains on the MEL 2 granule, a cytoplasmic ribonucleoprotein complex maintaining faithful meiosis progression in rice
M Mimura, S Ono, H Somashekar… - New …, 2024 - Wiley Online Library
Cytoplasmic ribonucleoprotein (RNP) granules are membraneless structures composed of
various RNAs and proteins that play important roles in post‐transcriptional regulation. While …
various RNAs and proteins that play important roles in post‐transcriptional regulation. While …
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules
PG Cipriani, O Bay, J Zinno, M Gutwein, HH Gan… - Elife, 2021 - elifesciences.org
We describe MIP-1 and MIP-2, novel paralogous C. elegans germ granule components that
interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule …
interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule …
RNA-binding proteins and post-transcriptional regulation in lens biology and cataract: Mediating spatiotemporal expression of key factors that control the cell cycle …
SA Lachke - Experimental eye research, 2022 - Elsevier
Abstract Development of the ocular lens–a transparent tissue capable of sustaining frequent
shape changes for optimal focusing power–pushes the boundaries of what cells can …
shape changes for optimal focusing power–pushes the boundaries of what cells can …
[HTML][HTML] Regulation of DNA methylation during the testicular development of Shaziling pigs
Y Anqi, Y Saina, C Chujie, Y Yanfei, T Xiangwei… - Genomics, 2022 - Elsevier
DNA methylation is one of the key epigenetic regulatory mechanisms in development and
spermatogenesis. However, the dynamic regulatory mechanisms of genome-wide DNA …
spermatogenesis. However, the dynamic regulatory mechanisms of genome-wide DNA …
A NYN domain protein directly interacts with DECAPPING1 and is required for phyllotactic pattern
M Schiaffini, C Chicois, A Pouclet, T Chartier… - Plant …, 2022 - academic.oup.com
In eukaryotes, general mRNA decay requires the decapping complex. The activity of this
complex depends on its catalytic subunit, DECAPPING2 (DCP2), and its interaction with …
complex depends on its catalytic subunit, DECAPPING2 (DCP2), and its interaction with …