Purpose To provide evidence-based guidance on the optimum prevention and treatment
approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) …

Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Chemotherapy induced peripheral neuropathy (CIPN) is a potentially dose limiting side
effect of commonly used chemotherapeutic agents like taxanes, vinca-alkaloids, platinum …

Background Neuropathy is a debilitating toxicity associated with various chemotherapy
agents. We evaluated the association between common comorbid conditions and the …

Purpose: Taxane-induced peripheral neuropathy (TIPN) is an important survivorship issue
for many cancer patients. Currently, there are no clinically implemented biomarkers to …

Background The long-term effects of chemotherapy are sparsely reported. Peripheral
neuropathy (PN) is one of the most frequent toxicities associated with taxane use for the …

Background Taxanes, including paclitaxel and docetaxel, are indispensable for treatment of
cancer. Development of toxicity frequently necessitates dose reduction or discontinuation of …

Purpose To determine the optimal dose and schedule of anthracycline and taxane
administration as adjuvant therapy for early-stage breast cancer. Patients and Methods A 2× …

Purpose: Associations between taxane-related sensory neuropathy (TRSN) and single-
nucleotide polymorphisms (SNP) have previously been reported, but few have been …

Breast cancer (BC) is one of the most prevalent types of cancer worldwide with high
morbidity and mortality rates. Treatment modalities include systemic therapy, in which …