New insights for oxidative stress and diabetes mellitus

K Maiese - Oxidative medicine and cellular longevity, 2015 - Wiley Online Library
The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Proanthocyanidins against oxidative stress: from molecular mechanisms to clinical applications

L Yang, D Xian, X Xiong, R Lai, J Song… - BioMed research …, 2018 - Wiley Online Library
Proanthocyanidins (PCs) are naturally occurring polyphenolic compounds abundant in
many vegetables, plant skins (rind/bark), seeds, flowers, fruits, and nuts. Numerous in vitro …

Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR

K Maiese - Neural regeneration research, 2016 - journals.lww.com
Throughout the globe, diabetes mellitus (DM) is increasing in incidence with limited
therapies presently available to prevent or resolve the significant complications of this …

FoxO transcription factors and regenerative pathways in diabetes mellitus

K Maiese - Current Neurovascular Research, 2015 - ingentaconnect.com
Mammalian forkhead transcription factors of the O class (FoxO) are exciting targets under
consideration for the development of new clinical entities to treat metabolic disorders and …

Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease

K Maiese - Neural regeneration research, 2015 - journals.lww.com
Diabetes mellitus affects almost 350 million individuals throughout the globe resulting in
significant morbidity and mortality. Of further concern is the growing population of individuals …

[HTML][HTML] mTOR: Driving apoptosis and autophagy for neurocardiac complications of diabetes mellitus

K Maiese - World Journal of Diabetes, 2015 - ncbi.nlm.nih.gov
Abstract The World Health Organization estimates that diabetes mellitus (DM) will become
the seventh leading cause of death during the next two decades. DM affects approximately …

Harnessing the power of SIRT1 and non-coding RNAs in vascular disease

K Maiese - Current neurovascular research, 2017 - ingentaconnect.com
Noncommunicable diseases (NCDs) contribute to a significant amount of disability and
death in the world. Of these disorders, vascular disease is ranked high, falls within the five …

[HTML][HTML] Calabash (Lagenaria siceraria) potency to ameliorate hyperglycemia and oxidative stress in diabetes

LYM Juee, AM Naqishbandi - Journal of Functional Foods, 2020 - Elsevier
Calabash fruit is traditionally used as an antidiabetic remedy in the Kurdistan region.
Different extracts (400 mg/kg) were investigated for antihyperglycemic potency on normal …

Programming apoptosis and autophagy with novel approaches for diabetes mellitus

K Maiese - Current Neurovascular Research, 2015 - ingentaconnect.com
According to the World Health Organization, diabetes mellitus (DM) in the year 2030 will be
ranked the seventh leading cause of death in the world. DM impacts all systems of the body …

The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice

C Xu, L Zhu, T Chan, X Lu, W Shen, MC Gillies… - PLoS One, 2015 - journals.plos.org
Diabetes mellitus is a chronic metabolic disorder that significantly affects human health and
well-being. The Solute carrier transporters (SLCs), particularly the Organic anion/cation …