Regulation of hypothalamic–pituitary–adrenocortical (HPA) axis activity by stress is a
fundamental survival mechanism and HPA-dysfunction is implicated in psychiatric disorders …

Research on the inter-relationship between drug abuse and social stress has primarily
focused on the role of stress exposure during adulthood and more recently, adolescence …

Evidence that childhood adversities are risk factors for psychosis has accumulated rapidly.
Research into the mechanisms underlying these relationships has focused, productively, on …

A growing body of evidence suggests that nucleus accumbens (NAc) plays a significant role
not only in the physiological processes associated with reward and satisfaction but also in …

Early-life stress is a critical risk factor for developing psychopathological alterations later in
life. This early adverse environment has been modeled in rats by exposure to stress during …

The maternal environment has a profound effect on the development of offspring, including
responses to stress mediated by the hypothalamic-pituitary-adrenal (HPA) axis. In rodents …

Epidemiological data indicate that early stress increases vulnerability to psychiatric
disorders, including anxiety and depression. In the present study we sought to investigate …

Different models of rodent maternal separation (MS) have been used to investigate long-
term neurobiological and behavioral changes, associated with early stress. However, few …

Early life trauma is a risk factor for a number of neuropsychiatric disorders, including
schizophrenia (SZ). The current study assessed how an early life traumatic event, maternal …

The modern concept of stress is based on responses to events or factors (“stressors”)
experienced as aversive, threatening or excessive for maintaining physiological equilibrium …