Recombinant protein-based injectable materials for biomedical applications

CG Garcia, SS Patkar, B Wang, R Abouomar… - Advanced Drug Delivery …, 2023 - Elsevier
Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

Synthetic biology-guided design and biosynthesis of protein polymers for delivery

KK Tian, ZG Qian, XX Xia - Advanced Drug Delivery Reviews, 2023 - Elsevier
Vehicles derived from genetically engineered protein polymers have gained momentum in
the field of biomedical engineering due to their unique designability, remarkable …

The construction of elastin-like polypeptides and their applications in drug delivery system and tissue repair

Y Guo, S Liu, D Jing, N Liu, X Luo - Journal of Nanobiotechnology, 2023 - Springer
Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural
elastin. These peptides have a low critical solution temperature phase behavior and can be …

Expanding the Genetic Code of Bioelectrocatalysis and Biomaterials

Y Chemla, F Kaufman, M Amiram, L Alfonta - Chemical Reviews, 2024 - ACS Publications
Genetic code expansion is a promising genetic engineering technology that incorporates
noncanonical amino acids into proteins alongside the natural set of 20 amino acids. This …

Engineered bacterial host for genetic encoding of physiologically stable protein nitration

NG Koch, T Baumann, JH Nickling… - Frontiers in Molecular …, 2022 - frontiersin.org
Across scales, many biological phenomena, such as protein folding or bioadhesion and
cohesion, rely on synergistic effects of different amino acid side chains at multiple positions …

Orthogonal translation with 5‐cyanotryptophan as an infrared probe for local structural information, electrostatics, and hydrogen bonding

GJ von Freiherr Sass, M Blain‐Hartung… - Protein …, 2023 - Wiley Online Library
Orthogonal translation is an efficient tool that provides many valuable spectral probes
capable of covering different parts of the electromagnetic spectrum and thus enabling …

Molecular design of protein-based materials–state of the art, opportunities and challenges at the interface between materials engineering and synthetic biology

E Shire, AAB Coimbra, CB Ostria… - … Systems Design & …, 2024 - pubs.rsc.org
Structural proteins like silk, squid ring teeth, elastin, collagen, or resilin, among others, are
inspiring the development of new sustainable biopolymeric materials for applications …

Robust Photocontrol of Elastin-like Polypeptide Phase Transition with a Genetically Encoded Arylazopyrazole

DS Strugach, D Hadar, M Amiram - ACS Synthetic Biology, 2023 - ACS Publications
The rational design of light-responsive proteins and protein-based polymers requires both a
photoswitch with suitable light-responsive properties and the ability to incorporate it at …

Self‐assembly of temperature‐responsive di‐block polypeptides functionalized with unnatural amino acids

R Azulay, DS Strugach, M Amiram - Protein Science, 2024 - Wiley Online Library
The incorporation of unnatural amino acids (uAAs) into protein‐based polymers has
emerged as a powerful methodology to expand their chemical repertoire. Recently, we …

OPEN ACCESS EDITED BY

EE Blaak, M Opperman, X Li, D Di… - Micronutrients and …, 2024 - books.google.com
Background: Cardiovascular disease (CVD) has become a key global health issue. Serum
carotenoids are associated with CVD, while their effects on different diseases remain …