Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …
arise as the disease progresses. A growing body of evidence suggests that pathological …
The influence of neuroinflammation in Autism Spectrum Disorder
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …
by deficits in social communication and restricted or repetitive behaviours. The clinical …
[HTML][HTML] Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease
S Pugazhenthi, L Qin, PH Reddy - … acta (BBA)-molecular basis of disease, 2017 - Elsevier
Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …
Systemic inflammation and microglial activation: systematic review of animal experiments
ICM Hoogland, C Houbolt, DJ van Westerloo… - Journal of …, 2015 - Springer
Background Animal studies show that peripheral inflammatory stimuli may activate
microglial cells in the brain implicating an important role for microglia in sepsis-associated …
microglial cells in the brain implicating an important role for microglia in sepsis-associated …
Hippocampal function is impaired by a short-term high-fat diet in mice: Increased blood–brain barrier permeability and neuroinflammation as triggering events
GC de Paula, HS Brunetta, DF Engel… - Frontiers in …, 2021 - frontiersin.org
Worldwide, and especially in Western civilizations, most of the staple diets contain high
amounts of fat and refined carbohydrates, leading to an increasing number of obese …
amounts of fat and refined carbohydrates, leading to an increasing number of obese …
Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity
F Calabrese, AC Rossetti, G Racagni… - Frontiers in cellular …, 2014 - frontiersin.org
Cytokines are key regulatory mediators involved in the host response to immunological
challenges, but also play a critical role in the communication between the immune and the …
challenges, but also play a critical role in the communication between the immune and the …
Post-operative cognitive dysfunction: an exploration of the inflammatory hypothesis and novel therapies
Abstract Post-Operative Cognitive Dysfunction (POCD) is a highly prevalent condition with
significant clinical, social and financial impacts for patients and their communities. The …
significant clinical, social and financial impacts for patients and their communities. The …
Neurodegenerative and neurological disorders by small inhaled particles
HJ Heusinkveld, T Wahle, A Campbell, RHS Westerink… - Neurotoxicology, 2016 - Elsevier
The world s population is steadily ageing and as a result, health conditions related to
ageing, such as dementia, have become a major public health concern. In 2001, it was …
ageing, such as dementia, have become a major public health concern. In 2001, it was …
Multiple sclerosis and cognition: synaptic failure and network dysfunction
M Di Filippo, E Portaccio, A Mancini… - Nature Reviews …, 2018 - nature.com
Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …
(MS), with important implications for the everyday life of individuals with MS and for disease …
Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation
Q Liu, YM Sun, H Huang, C Chen, J Wan… - Journal of …, 2021 - Springer
Background Postoperative cognitive dysfunction (POCD) is a very common complication that
might increase the morbidity and mortality of elderly patients after surgery. However, the …
might increase the morbidity and mortality of elderly patients after surgery. However, the …