The classical role of AMP-activated protein kinase (AMPK) is as a cellular energy sensor
activated by falling energy status, signalled by increases in AMP to ATP and ADP to ATP …

The AMPK (AMP-activated protein kinase) and TOR (target-of-rapamycin) pathways are
interlinked, opposing signaling pathways involved in sensing availability of nutrients and …

Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

Mammalian AMPK is known to be activated by falling cellular energy status, signaled by
rising AMP/ATP and ADP/ATP ratios. We review recent information about how this occurs …

The major energy source for most cells is glucose, from which ATP is generated via
glycolysis and/or oxidative metabolism. Glucose deprivation activates AMP-activated protein …

AMP-activated protein kinase (AMPK) is a key regulator of energy balance expressed
ubiquitously in eukaryotic cells. Here we review the canonical adenine nucleotide …

Mitochondrial reactive oxygen species (ROS) production is a tightly regulated redox signal
that transmits information from the organelle to the cell. Other mitochondrial signals, such as …

Long-chain fatty acids (LCFAs) play important roles in cellular energy metabolism, acting as
both an important energy source and signalling molecules. LCFA-CoA esters promote their …

Cellular ROS production participates in various cellular functions but its accumulation
decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant …

The AMP-activated protein kinase (AMPK) is a key regulator of cellular and whole-body
energy homeostasis, which acts to restore energy homoeostasis whenever cellular energy …