Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials

J Liu, Y Wang, Y Akamatsu, CC Lee, RA Stetler… - Progress in …, 2014 - Elsevier
The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …

Protecting the ischaemic penumbra as an adjunct to thrombectomy for acute stroke

JC Baron - Nature Reviews Neurology, 2018 - nature.com
After ischaemic stroke, brain damage can be curtailed by rescuing the 'ischaemic penumbra'—
that is, the severely hypoperfused, at-risk but not yet infarcted tissue. Current evidence …

The cerebral collateral circulation: relevance to pathophysiology and treatment of stroke

MD Ginsberg - Neuropharmacology, 2018 - Elsevier
The brain's collateral circulation consists of arterial anastomotic channels capable of
providing nutrient perfusion to brain regions whose normal sources of flow have become …

Worse stroke outcome in atrial fibrillation is explained by more severe hypoperfusion, infarct growth, and hemorrhagic transformation

HTH Tu, BCV Campbell… - … Journal of Stroke, 2015 - journals.sagepub.com
Background Atrial fibrillation is associated with greater baseline neurological impairment
and worse outcomes following ischemic stroke. Previous studies suggest that greater …

Expanding the concept of neuroprotection for acute ischemic stroke: the pivotal roles of reperfusion and the collateral circulation

MD Ginsberg - Progress in neurobiology, 2016 - Elsevier
This review surveys the efforts taken to achieve clinically efficacious protection of the
ischemic brain and underscores the necessity of expanding our purview to include the …

Cerebral collaterals and collateral therapeutics for acute ischemic stroke

IR Winship - Microcirculation, 2015 - Wiley Online Library
Cerebral collaterals are vascular redundancies in the cerebral circulation that can partially
maintain blood flow to ischemic tissue when primary conduits are blocked. After occlusion of …

Pharyngeal electrical stimulation for treatment of poststroke dysphagia: individual patient data meta‐analysis of randomised controlled trials

P Scutt, HS Lee, S Hamdy… - Stroke research and …, 2015 - Wiley Online Library
Background. Dysphagia after stroke is common, associated independently with poor
outcome, and has limited treatment options. Pharyngeal electrical stimulation (PES) is a …

Collaterals: Implications in cerebral ischemic diseases and therapeutic interventions

Y Nishijima, Y Akamatsu, PR Weinstein, J Liu - Brain research, 2015 - Elsevier
Despite the tremendous progress made in the treatment of cerebrovascular occlusive
diseases, many patients suffering from ischemic brain injury still experience dismal …

Experimental activation of the sphenopalatine ganglion provokes cluster-like attacks in humans

HW Schytz, M Barløse, S Guo, J Selb… - …, 2013 - journals.sagepub.com
Background High frequency (HF) stimulation of the sphenopalatine ganglion (SPG) is an
emerging abortive treatment for cluster headache (CH) attacks. HF SPG stimulation is …

Cerebral collateral circulation in experimental ischemic stroke

E Cuccione, G Padovano, A Versace… - … & translational stroke …, 2016 - Springer
Cerebral collateral circulation is a subsidiary vascular network, which is dynamically
recruited after arterial occlusion, and represents a powerful determinant of ischemic stroke …