Background Acacetin is a di-hydroxy and mono-methoxy flavone present in various plants,
including black locust, Damiana, Silver birch. Literature information revealed that acacetin …

Altered expression and function of the transcription factor cyclic AMP response-binding
protein (CREB) has been identified to play an important role in cancer and is associated with …

Melanin, the compound primarily responsible in humans for hair, eye and skin pigmentation,
is produced by melanocytes through a complicated process called melanogenesis that is …

Skin cancer is a life threatening disease and their prevalence and risk has been increasing
over the past three decades causing significant loss to human health worldwide. Mostly skin …

Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

Introduction Tyrosinase is a multifunctional copper‐containing oxidase enzyme that
catalyses the first steps in the formation of melanin pigments. Identification of tyrosinase …

Skin is the largest human organ, our protection against various environmental assaults and
noxious agents. Accumulation of these stress events may lead to the formation of skin …

Melanoma claims approximately 80% of skin cancer-related deaths. Its life-threatening
nature is primarily due to a propensity to metastasize. The prognosis for melanoma patients …

Human skin is continuously subjected to environmental stresses, as well as extrinsic and
intrinsic noxious agents. Although skin adopts various molecular mechanisms to maintain …

Chromolaena odorata, commonly known as Siam weed, is popular as a traditional medicine.
We report the isolation and characterization of four compounds from a cytotoxic fraction, F …