The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …

Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …

Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …

Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

Astrocyte activation and reactive gliosis accompany most of the pathologies in the brain,
spinal cord, and retina. Reactive gliosis has been described as constitutive, graded, multi …

Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Astrocytes maintain the homeostasis of the central nervous system (CNS) by eg recycling of
neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …

Stroke is an acute insult to the central nervous system (CNS) that triggers a sequence of
responses in the acute, subacute as well as later stages, with prominent involvement of …

Müller cells are active players in normal retinal function and in virtually all forms of retinal
injury and disease. Reactive Müller cells protect the tissue from further damage and …

Multiple sclerosis (MS) is an inflammatory disorder causing central nervous system (CNS)
demyelination and axonal injury. Although its etiology remains elusive, several lines of …