Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods
S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …
Biocatalysis making waves in organic chemistry
U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …
biocatalysis has developed, and in doing so changed our perception of what organic …
[HTML][HTML] Using inorganic nanoparticles to fight fungal infections in the antimicrobial resistant era
T Huang, X Li, M Maier, NM O'Brien-Simpson… - Acta Biomaterialia, 2023 - Elsevier
Fungal infections pose a serious threat to human health and livelihoods. The number and
variety of clinically approved antifungal drugs is very limited, and the emergence and rapid …
variety of clinically approved antifungal drugs is very limited, and the emergence and rapid …
[HTML][HTML] Influence of exogenous elicitors on the production of secondary metabolite in plants: A review (“VSI: secondary metabolites”)
During the whole lifespan from seedling to the mature stage, the plant produces a range of
complex compounds usually known as Secondary Metabolites (SMs) for their cellular and …
complex compounds usually known as Secondary Metabolites (SMs) for their cellular and …
[图书][B] Natural product biosynthesis
CT Walsh, Y Tang - 2017 - books.google.com
Authored by leading experts in the enzymology of natural product biosynthesis, this textbook
provides a thorough description of the types of natural products, the biosynthetic pathways …
provides a thorough description of the types of natural products, the biosynthetic pathways …
Recent advancements in microbial polysaccharides: Synthesis and applications
YAG Mahmoud, ME El-Naggar, A Abdel-Megeed… - Polymers, 2021 - mdpi.com
Polysaccharide materials are widely applied in different applications including food, food
packaging, drug delivery, tissue engineering, wound dressing, wastewater treatment, and …
packaging, drug delivery, tissue engineering, wound dressing, wastewater treatment, and …
A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond
Psychedelic mushrooms containing psilocybin and related tryptamines have long been used
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …
Discovery and engineering of the cocaine biosynthetic pathway
YJ Wang, JP Huang, T Tian, Y Yan… - Journal of the …, 2022 - ACS Publications
Cocaine, the archetypal tropane alkaloid from the plant genus Erythroxylum, has recently
been used clinically as a topical anesthesia of the mucous membranes. Despite this, the key …
been used clinically as a topical anesthesia of the mucous membranes. Despite this, the key …
Palladium-catalyzed decarboxylation [2+ 2+ 2] annulation approach to chromone-containing polycyclic compounds
YC Fang, JH Chen, RF Xiu, LR Zhang… - Organic Chemistry …, 2023 - pubs.rsc.org
We present herein a palladium-catalyzed decarboxylation [2+ 2+ 2] annulation with 3-
iodochromones, bridged olefins, and o-bromobenzoic acids to give various exo-chromone …
iodochromones, bridged olefins, and o-bromobenzoic acids to give various exo-chromone …
Engineered production of strictosidine and analogues in yeast
J Misa, JM Billingsley, K Niwa, RK Yu… - ACS synthetic …, 2022 - ACS Publications
Monoterpene indole alkaloids (MIAs) are an expansive class of plant natural products, many
of which have been named on the World Health Organization's List of Essential Medicines …
of which have been named on the World Health Organization's List of Essential Medicines …