A pathophysiological framework of hippocampal dysfunction in ageing and disease

SA Small, SA Schobel, RB Buxton, MP Witter… - Nature Reviews …, 2011 - nature.com
The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

Working memory, long-term memory, and medial temporal lobe function

A Jeneson, LR Squire - Learning & memory, 2012 - learnmem.cshlp.org
Early studies of memory-impaired patients with medial temporal lobe (MTL) damage led to
the view that the hippocampus and related MTL structures are involved in the formation of …

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

UA Khan, L Liu, FA Provenzano, DE Berman… - Nature …, 2014 - nature.com
The entorhinal cortex has been implicated in the early stages of Alzheimer's disease, which
is characterized by changes in the tau protein and in the cleaved fragments of the amyloid …

Evidence for grid cells in a human memory network

CF Doeller, C Barry, N Burgess - Nature, 2010 - nature.com
Grid cells in the entorhinal cortex of freely moving rats provide a strikingly periodic
representation of self-location which is indicative of very specific computational …

Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation …

PA Yushkevich, RSC Amaral, JC Augustinack… - Neuroimage, 2015 - Elsevier
Objective An increasing number of human in vivo magnetic resonance imaging (MRI)
studies have focused on examining the structure and function of the subfields of the …

The hippocampus supports multiple cognitive processes through relational binding and comparison

RK Olsen, SN Moses, L Riggs, JD Ryan - Frontiers in human …, 2012 - frontiersin.org
It has been well established that the hippocampus plays a pivotal role in explicit long-term
recognition memory. However, findings from amnesia, lesion and recording studies with non …

A unified framework for the functional organization of the medial temporal lobes and the phenomenology of episodic memory

C Ranganath - Hippocampus, 2010 - Wiley Online Library
There is currently an intense debate about the nature of recognition memory and about the
roles of medial temporal lobe subregions in recognition memory processes. At a larger level …

Global similarity and pattern separation in the human medial temporal lobe predict subsequent memory

KF LaRocque, ME Smith, VA Carr… - Journal of …, 2013 - Soc Neuroscience
Intense debate surrounds the role of medial temporal lobe (MTL) structures in recognition
memory. Using high-resolution fMRI and analyses of pattern similarity in humans, we …

Development of hippocampal–prefrontal cortex interactions through adolescence

FJ Calabro, VP Murty, M Jalbrzikowski… - Cerebral …, 2020 - academic.oup.com
Significant improvements in cognitive control occur from childhood through adolescence,
supported by the maturation of prefrontal systems. However, less is known about the neural …

The role of experience in adolescent cognitive development: Integration of executive, memory, and mesolimbic systems

VP Murty, F Calabro, B Luna - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Adolescence marks a time of unique neurocognitive development, in which executive
functions reach adult levels of maturation. While many core facets of executive function may …