Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …

The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …

The human body is colonized by a diverse collective of microorganisms, including bacteria,
fungi, protozoa and viruses. The smallest entity of this microbial conglomerate are the …

Background Substantial efforts have been made to link the gut bacterial community to many
complex human diseases. Nevertheless, the gut phages are often neglected. Results In this …

Introduction Convection-enhanced delivery (CED) is a method of targeted, local drug
delivery to the central nervous system (CNS) that bypasses the blood-brain barrier (BBB) …

Convection-enhanced delivery (CED) is a promising technique that generates a pressure
gradient at the tip of an infusion catheter to deliver therapeutics directly through the …

The human body is a large reservoir for bacterial viruses known as bacteriophages
(phages), which participate in dynamic interactions with their bacterial and human hosts that …

Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …

Convection-enhanced delivery (CED) is a bulk flow–driven process. Its properties permit
direct, homogeneous, targeted perfusion of CNS regions with putative therapeutics while …

The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …