Use of inactivated poliovirus vaccine for poliovirus outbreak response

AS Bandyopadhyay, RL Cavestany… - The Lancet Infectious …, 2024 - thelancet.com
With continued wild poliovirus transmission in Afghanistan and Pakistan and circulating
vaccine-derived poliovirus in certain countries, there exists an ongoing risk of importation of …

[HTML][HTML] Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022

NS Zuckerman, I Bar-Or, D Sofer, E Bucris… - …, 2022 - eurosurveillance.org
We report an emergence and increase in poliovirus type 2 detection via routine wastewater
surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April …

[HTML][HTML] Plant-made poliovirus vaccines–Safe alternatives for global vaccination

OC Bolaños-Martínez, R Strasser - Frontiers in Plant Science, 2022 - frontiersin.org
Human polioviruses are highly infectious viruses that are spread mainly through the fecal-
oral route. Infection of the central nervous system frequently results in irreversible paralysis …

Evaluation of the safety, immunogenicity, and faecal shedding of novel oral polio vaccine type 2 in healthy newborn infants in Bangladesh: a randomised, controlled …

K Zaman, AS Bandyopadhyay, M Hoque, C Gast… - The Lancet, 2023 - thelancet.com
Background Type 2 circulating vaccine-derived polioviruses (cVDPV2) from Sabin oral
poliovirus vaccines (OPVs) are the leading cause of poliomyelitis. A novel type 2 OPV …

[HTML][HTML] Choosing the right path toward polio eradication

K Chumakov, C Brechot, RC Gallo… - New England Journal of …, 2023 - Mass Medical Soc
Choosing the Right Path toward Polio Eradication Continued circulation of wild and
attenuated polioviruses suggests that our eradication campaign needs reevaluation. Long …

Plugging the medical brain drain

A Kamarulzaman, K Ramnarayan, AO Mocumbi - The Lancet, 2022 - thelancet.com
that vaccine-derived poliovirus can emerge in such settings and underline the importance of
implementing effective environmental surveillance in countries where it is not currently in …

Immune persistence of an inactivated poliovirus vaccine derived from the Sabin strain: a 10-year follow-up of a phase 3 study

L Ma, Z Ying, W Cai, J Wang, J Zhou, H Yang… - …, 2023 - thelancet.com
Background In a previous phase 3 clinical trial, we showed that an inactivated poliovirus
vaccine derived from the Sabin strain (sIPV) can induce neutralising antibodies against …

[HTML][HTML] Effect of maternal immunisation with multivalent vaccines containing inactivated poliovirus vaccine (IPV) on infant IPV immune response: A phase 4, multi …

NC Grassly, N Andrews, G Cooper, L Stephens… - Vaccine, 2023 - Elsevier
Multivalent diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine
(DTaP/IPV) has been offered to pregnant women in the United Kingdom since 2012. To …

Poliomyelitis is a current challenge: long-term sequelae and circulating vaccine-derived poliovirus

J Quarleri - Geroscience, 2023 - Springer
For more than 20 years, the World Health Organization Western Pacific Region (WPR) has
been polio-free. However, two current challenges are still polio-related. First, around half of …

Detection of poliovirus in London highlights the value of sewage surveillance

M Hill, AJ Pollard - The Lancet, 2022 - thelancet.com
The discovery of poliovirus in London wastewater has garnered wide public interest and
media attention. It serves as a reminder that until the virus is eradicated from the world, all …