Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a poor
prognosis, despite surgical resection combined with radio-and chemotherapy. The major …

Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

As the cornerstone of high-grade glioma (HGG) treatment, radiotherapy temporarily controls
tumor cells via inducing oxidative stress and subsequent DNA breaks. However, almost all …

MicroRNAs (miRNAs) are small and non-coding RNAs that display aberrant expression in
the tissue and plasma of cancer patients when tested in comparison to healthy individuals …

MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …

Notorious for its high mortality rate, the current standard treatment for high-grade gliomas
remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled …

Background: Chemotherapy is one of the most common therapies used in the treatment of
colorectal cancer (CRC), but chemoresistance inevitably occurs. It is challenging to obtain …

The risk of cancer in schizophrenia has been controversial. Confounders of the issue are
cigarette smoking in schizophrenia, and antiproliferative effects of antipsychotic medications …

Background: Glioma is the primary cancer of the central nervous system in adults. Among
gliomas, glioblastoma is the most deadly and aggressive form, with an average life span of 1 …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene
expression at the post-transcriptional level. It has been reported that microRNA-144 (miR …