Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Background Hepatosteatosis is the earliest stage in the pathogenesis of nonalcoholic fatty
(NAFLD) and alcoholic liver disease (ALD). As NAFLD is affecting 10–24% of the general …

Cardiovascular disease is the main cause of early death in the settings of chronic kidney
disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be …

The diverse nature of intestinal alkaline phosphatase (IAP) functions has remained elusive,
and it is only recently that four additional major functions of IAP have been revealed. The …

THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

This study examined the effectiveness of a DNA vaccine for S. agalactiae that was delivered
by mannose-based polyethyleneimine (Man-PEI). The results showed that Man-PEI/pcDNA …

Sepsis is a life-threatening inflammatory syndrome accompanying a bloodstream infection.
Frequently secondary to pathogenic bacterial infections, sepsis remains difficult to treat as a …

Alkaline phosphatases (Alps) are well-studied enzymes that remove phosphates from a
variety of substrates. Alps function in diverse biological processes, including modulating …

The baculovirus expression vector system (BEVS) is a widely used platform for the
production of recombinant eukaryotic proteins. However, the BEVS has limitations in …

Cardiac surgery with cardiopulmonary bypass provokes a systemic inflammatory response
syndrome caused by the surgical trauma itself, blood contact with the non-physiological …