Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases

CG Vazhappilly, SA Ansari, R Al-Jaleeli… - …, 2019 - Springer
The failure of mechanisms of natural anti-coagulation either due to genetic impairment or
due to severe external injuries may result in a condition called thrombosis. This is believed …

Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress

S Rahman, S Mathew, P Nair, WS Ramadan… - …, 2021 - Springer
Berries are natural sources of anthocyanins, especially cyanidin-3-glucoside (C3G), and
exhibit significant antioxidant, antidiabetic, anti-inflammatory, and cytoprotective effects …

Role of dietary antioxidants in p53‐mediated cancer chemoprevention and tumor suppression

JPJ Merlin, HPV Rupasinghe… - … Medicine and Cellular …, 2021 - Wiley Online Library
Cancer arises through a complex interplay between genetic, behavioral, metabolic, and
environmental factors that combined trigger cellular changes that over time promote …

Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment

CG Vazhappilly, M Amararathna, AC Cyril… - The Journal of …, 2021 - Elsevier
Over the last two decades, several advancements have been made to improve the
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …

Phenolic compounds and antioxidant status of cookies supplemented with apple pomace

M Kruczek, D Gumul, A Korus, K Buksa, R Ziobro - Antioxidants, 2023 - mdpi.com
The post-production leftovers after the pressing of apple juice are a rich source of health-
promoting compounds, which could be used in the food industry for the manufacture of …

Polyphenols: Major regulators of key components of DNA damage response in cancer

M Majidinia, A Bishayee, B Yousefi - DNA repair, 2019 - Elsevier
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …

Effect of natural food antioxidants against LDL and DNA oxidative changes

S Kiokias, C Proestos, V Oreopoulou - Antioxidants, 2018 - mdpi.com
Radical oxygen species formed in human tissue cells by many endogenous and exogenous
pathways cause extensive oxidative damage which has been linked to various human …

[HTML][HTML] Natural products for combating multidrug resistance in cancer

T Chen, Z Xiao, X Liu, T Wang, Y Wang, F Ye… - Pharmacological …, 2024 - Elsevier
Cancer cells frequently develop resistance to chemotherapeutic therapies and targeted
drugs, which has been a significant challenge in cancer management. With the growing …

[HTML][HTML] The relationship between standard reduction potentials of catechins and biological activities involved in redox control

M Baranowska, K Suliborska, W Chrzanowski… - Redox Biology, 2018 - Elsevier
Redox homeostasis involves factors that ensure proper function of cells. The excess reactive
oxygen species (ROS) leads to oxidative stress and increased risk of oxidative damage to …

Role of antioxidant vitamins and other micronutrients on regulations of specific genes and signaling pathways in the prevention and treatment of cancer

OF Fagbohun, CR Gillies, KPJ Murphy… - International Journal of …, 2023 - mdpi.com
Cancer is an escalating global issue, with 19.3 million new cases and 9.9 million deaths in
2020. Therefore, effective approaches to prevent cancer are urgently required. Diet plays a …