[PDF][PDF] GDF15: a hormone conveying somatic distress to the brain
GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …
[HTML][HTML] GDF-15, a future therapeutic target of glucolipid metabolic disorders and cardiovascular disease
QA Xiao, Q He, J Zeng, X Xia - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Growth and differentiation factor 15 (GDF-15) was discovered as a member of the
transforming growth factor β (TGF-β) superfamily and the serum level of GDF-15 was …
transforming growth factor β (TGF-β) superfamily and the serum level of GDF-15 was …
Changes in systemic GDF15 across the adult lifespan and their impact on maximal muscle power: the Copenhagen Sarcopenia Study
J Alcazar, U Frandsen, T Prokhorova… - Journal of Cachexia …, 2021 - Wiley Online Library
Background Although growth differentiation factor 15 (GDF15) is known to increase with
disease and is associated with low physical performance, the role of GDF15 in normal …
disease and is associated with low physical performance, the role of GDF15 in normal …
Association of GDF15 with inflammation and physical function during aging and recovery after acute hospitalization: a longitudinal study of older patients and age …
J Tavenier, LJH Rasmussen… - The Journals of …, 2021 - academic.oup.com
Abstract Growth differentiation factor 15 (GDF15) is a stress-induced cytokine. Its plasma
levels increase during aging and acute illness. In older Patients and age-matched Controls …
levels increase during aging and acute illness. In older Patients and age-matched Controls …
Older adults with frailty syndrome present an altered platelet function and an increased level of circulating oxidative stress and mitochondrial dysfunction biomarker …
Introduction The elderly population is increasing worldwide and in Chile, it is expected to
grow rapidly. The World Health Organization (WHO) ICOPE guideline (Integrated Care for …
grow rapidly. The World Health Organization (WHO) ICOPE guideline (Integrated Care for …
Relation of low lymphocyte count to frailty and its usefulness as a prognostic biomarker in patients> 65 years of age with acute coronary syndrome
J Núñez, C Sastre, G D'Ascoli, V Ruiz… - The American Journal of …, 2020 - Elsevier
Low lymphocyte count, as a marker of inflammation and immunosuppression, may be useful
for identifying frail patients. In this work, we aimed to evaluate the association between low …
for identifying frail patients. In this work, we aimed to evaluate the association between low …
Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study
DGJ McKechnie, AO Papacosta, LT Lennon… - Experimental …, 2021 - Elsevier
Background/objectives Subclinical cardiovascular disease (CVD) is cross-sectionally
associated with frailty, but the relationship between subclinical CVD and incident frailty has …
associated with frailty, but the relationship between subclinical CVD and incident frailty has …
Prognostic value of growth differentiation factor-15 in patients with coronary artery disease: A meta-analysis and systematic review
S Zhang, P Hao, J Li, Q Zhang, X Yin… - Frontiers in …, 2023 - frontiersin.org
Background and aims The predictive value of growth differentiation factor-15 (GDF-15) for
individual cardiovascular outcomes remained controversial in patients with coronary artery …
individual cardiovascular outcomes remained controversial in patients with coronary artery …
Growth differentiation factor 15 in severe aortic valve stenosis: relationship with left ventricular remodeling and frailty
I Fabiani, T Santoni, M Angelillis, S Petricciuolo… - Journal of clinical …, 2020 - mdpi.com
Background: Frailty is an important outcome predictor in patients with aortic stenosis who
are candidates for transcatheter or surgical aortic valve replacement (AVR) …
are candidates for transcatheter or surgical aortic valve replacement (AVR) …
Prospective associations of plasma growth differentiation factor 15 with physical performance and cognitive functions in older adults
L He, P de Souto Barreto… - The Journals of …, 2022 - academic.oup.com
Background Growth differentiation factor 15 (GDF15) has been associated with several age-
related disorders, but its associations with functional abilities in community-dwelling older …
related disorders, but its associations with functional abilities in community-dwelling older …