Health benefits of phytochemicals from Brazilian native foods and plants: Antioxidant, antimicrobial, anti-cancer, and risk factors of metabolic/endocrine disorders …

APA de Carvalho, CA Conte-Junior - Trends in Food Science & Technology, 2021 - Elsevier
Background Brazil has over 40,000 varied plant species rich in phytochemicals, expressing
20% of the world's flora. Due to its immense diversity, Brazil presents a high potential to …

Recent updates on computer-aided drug discovery: time for a paradigm shift

T Usha, D Shanmugarajan, AK Goyal… - Current topics in …, 2017 - ingentaconnect.com
Computer-Aided Drug Designing (CADD) has gained a wide popularity among biologists
and chemists as a part of interdisciplinary drug discovery approach. It plays a vital role in the …

Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates

J Robitaille, VS Langlois - General and comparative endocrinology, 2020 - Elsevier
In 1974, a lack of 5α-dihydrotestosterone (5α-DHT), the most potent androgen across
species except for fish, was shown to be the origin of a type of pseudohermaphrodism in …

The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin …

NJ Sadgrove - Journal of ethnopharmacology, 2018 - Elsevier
Ethnopharmacological relevance Research in the past half a century has gradually sketched
the biological mechanism leading to androgenetic alopecia (AGA). Until recently the …

Molecular Docking and Quantum Mechanical Studies on Pelargonidin‐3‐Glucoside as Renoprotective ACE Inhibitor

T Usha, P Tripathi, V Pande… - International Scholarly …, 2013 - Wiley Online Library
Background and Aim. Despite tangible progress in recent years, substantial therapeutic
challenges remain unexplored in nephropathy, particularly in diabetic patient. Addressing …

Homology modeling of 5-alpha-reductase 2 using available experimental data

J Shamsara - Interdisciplinary Sciences: Computational Life …, 2019 - Springer
Alpha-reductase 2 is an interesting pharmaceutical target for the treatment of several
diseases, including prostate cancer, benign prostatic hyperplasia, male pattern baldness …

Exploring polypharmacology of some natural products using similarity search target fishing approach

IM Almasri - … Journal of Computational Biology and Drug …, 2018 - inderscienceonline.com
Natural products have long been considered as important sources for drug discovery due to
the diversity of their chemical structures and broad range of biological activities attained by …

[PDF][PDF] Molecular Docking and Quantum Mechanical Studies on Pelargonidin-3-Glucoside as Renoprotective ACE...

U Talambedu, P Tripathi, V Pande, SK Middha - 2013 - academia.edu
Background and Aim. Despite tangible progress in recent years, substantial therapeutic
challenges remain unexplored in nephropathy, particularly in diabetic patient. Addressing …

[PDF][PDF] Research Article Molecular Docking and Quantum Mechanical Studies on Pelargonidin-3-Glucoside as Renoprotective ACE Inhibitor

T Usha, P Tripathi, V Pande, SK Middha - 2013 - academia.edu
Background and Aim. Despite tangible progress in recent years, substantial therapeutic
challenges remain unexplored in nephropathy, particularly in diabetic patient. Addressing …